Pathology of US Porcine Epidemic Diarrhea Virus Strain PC21A in Gnotobiotic Pigs

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Jung, Kwonil ; Wang, Qiuhong ; Scheuer, Kelly A. ; Lu, Zhongyan ; Zhang, Yan ; Saif, Linda J.
• Description:
  To understand the progression of porcine epidemic diarrhea virus infection, we inoculated gnotobiotic pigs with a newly emerged US strain, PC21A, of the virus. At 24-48 hours postinoculation, the pigs exhibited severe diarrhea and vomiting, fecal shedding, viremia, and severe atrophic enteritis. These findings confirm that strain PC21A is highly enteropathogenic.
• Subjects:
  Dispatch Porcine Epidemic Diarrhea, Pathogenesis, Outbreak, USA, Gnotobiotic Pigs, US Strain, Pigs, Strain PC21A, Viruses, Enteropathogenic Porcine Epidemic Diarrhea Virus
• Source:
  Emerg Infect Dis. 20(4):662-665.
• Document Type:
  Journal Article
• Volume:
  20
• Issue:
  4
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:c0bedbeb8c432de667be3e686ad3664d20cca61a3ac4df3d884dc432d379f5b8
• Download URL:
  https://stacks.cdc.gov/view/cdc/22225/cdc_22225_DS1.pdf
• File Type:
  [PDF - 385.69 KB ]