Characterizing Dynamic Atmosphere Generation System Performance For Analytical Method Development.

Details

• Alternative Title:
  Journal of Occupational and Environmental Hygiene, 2025, v. 22, no. 2: Characterizing Dynamic Atmosphere Generation System Performance For Analytical Method Development.
• Journal Article:
  Journal of Occupational and Environmental Hygiene
• Personal Author:
  Doepke, Amos ; Streicher, Robert P. ; Shaw, Peter B. ; Andrews, Ronnee N. ; Farwick, Dawn R. ; Westbrook, Emily G. ; Roberts, Jennifer L. ; O'Connor, Paula F. ; Stastny, Angela L. ; Kulkarni, Pramod S.
• Description:
  A significant portion of the work of developing and validating methods for volatile organic compound (VOC) sampling in workplace atmospheres involves the use of laboratory-generated atmospheres. The sample variability was evaluated from the dynamic atmosphere generation system used for VOC atmosphere generation and sampling. Characterization of the bias and variability of samples was done for a variety of atmospheres containing neat n-heptane and mixtures of VOCs sampled on activated coconut shell charcoal. Estimates of sampling variability ranged from 2% for neat n-heptane to 12% for a component in the 10 VOC mix. Sample variability increased for lower concentration samples and for mixtures of VOCs compared to single component atmospheres. This study can serve as a baseline for future atmosphere sampling experiments evaluating performance at lower concentrations and mixed VOC environments.
• Content Notes:
  Author manuscript
• Subjects:
  • Volatile Organic Compounds
  • Environmental Monitoring
  • Air Pollutants, Occupational
  • Charcoal
• Keywords:
  • Air sampling
  • coconut shell charcoal
  • sample variability
  • VOC
  • volatile organic compound
• Source:
  Journal of Occupational and Environmental Hygiene, 2025, v. 22, no. 2
• DOI:
  https://doi.org/10.1080/15459624.2024.2423749
• ISSN:
  1545-9624 ; 1545-9632
• Pubmed ID:
  39631035
• Pubmed Central ID:
  PMC11842196
• Document Type:
  Text
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Genre:
  Journal Article
• Pages in Document:
  110-122 (26 pdf pages)
• Volume:
  22
• Issue:
  2
• Download URL:
  https://stacks.cdc.gov/view/cdc/261886/cdc_261886_DS1.pdf
• File Type:
  [PDF - 1.74 MB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:a70d6fab231843b42d8ed0e9e959669bedad6febe7e4123c96c85afc6f3545fef3a5f8b1564840ca883a40f7d10533c2112a6330f0db62e1af07ead8023ea5b8