Characterizing Dynamic Atmosphere Generation System Performance for Analytical Method Development

Details

• Personal Author:
  Andrews, Ronnee N. ; Doepke A ; Farwick DR ; Kulkarni PS ; O'Connor PF ; Roberts JL ; Shaw, Peter B. ; Stastny AL ; Streicher, Robert P. ; Westbrook EG
• Description:
  A significant portion of the work of developing and validating methods for volatile organic compound (VOC) sampling in workplace atmospheres involves the use of laboratory-generated atmospheres. The sample variability was evaluated from the dynamic atmosphere generation system used for VOC atmosphere generation and sampling. Characterization of the bias and variability of samples was done for a variety of atmospheres containing neat n-heptane and mixtures of VOCs sampled on activated coconut shell charcoal. Estimates of sampling variability ranged from 2% for neat n-heptane to 12% for a component in the 10 VOC mix. Sample variability increased for lower concentration samples and for mixtures of VOCs compared to single component atmospheres. This study can serve as a baseline for future atmosphere sampling experiments evaluating performance at lower concentrations and mixed VOC environments. [Description provided by NIOSH]
• Subjects:
  Environmental Monitoring Occupational Health Safety Volatile Organic Compounds
• Keywords:
  Air Sampling Techniques Analytical Methods Author Keywords: Air Sampling Coconut Shell Charcoal Exposure Assessment Sample Variability Sampling Equipment VOC VOCs Volatile Organic Compound Volatile Organic Compounds

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• ISSN:
  1545-9624
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Chicago Region [OSHA] ; Ohio
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  110-122
• Volume:
  22
• Issue:
  2
• NIOSHTIC Number:
  nn:20070366
• Citation:
  J Occup Environ Hyg 2025 Feb; 22(2):110-122
• Contact Point Address:
  Amos Doepke, Health Effects Laboratory Division, Chemical and Biological Monitoring Branch, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Cincinnati, Ohio
• Email:
  adoepke@cdc.gov
• Federal Fiscal Year:
  2025
• Peer Reviewed:
  True
• Source Full Name:
  Journal of Occupational and Environmental Hygiene
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:6b686adb1261f7d6488880f18644f7a6901d28a891a36c559c16ffca1b9ce79c1277b85bdd338e48e973700d5cce62cbebae7dd2ffb3d5ff32b54ce39af61615
• Download URL:
  https://stacks.cdc.gov/view/cdc/208597/cdc_208597_DS1.pdf
• File Type:
  [PDF - 1.57 MB ]