Trends in Costs of Routinely Recommended Vaccines in the United States, 2001-2023.

Details

• Alternative Title:
  Vaccine, 2025, v. 47: Trends in Costs of Routinely Recommended Vaccines in the United States, 2001-2023.
• Journal Article:
  Vaccine
• Personal Author:
  Kaul, RajReni ; Leidner, Andrew J. ; Chesson, Harrell W.
• Description:
  Economic models assessing vaccinations commonly assume that inflation-adjusted vaccine costs are constant over time. This study assessed this assumption using historical vaccine cost data.
  
  Private sector and CDC contracted vaccine cost data (2001-2023) were collected from the CDC Vaccine Price List and converted to US$2023 to adjust for inflation. Trends in inflation-adjusted costs were described, and the annual percent changes in costs were calculated for each vaccine.
  
  Changes in cost varied by vaccine. The average inflation-adjusted private sector costs increased by 0.9 % (IQR: -0.4 %-2.6 %) and 1.4 % (IQR: -0.4 %-3.2 %) annually among pediatric and adult vaccines, respectively, while CDC contracted costs increased by 0.9 % (IQR: 0.2 %-1.2 %) and 1.0 % (IQR: -0.8 %-2.1 %) annually among pediatric and adult vaccines, respectively.
  
  Inflation-adjusted vaccine costs increased on average since 2001, highlighting limitations of constant cost assumptions. These findings can inform cost-effectiveness analyses of multi-year vaccination programs and policies.
• Content Notes:
  Author manuscript
• Subjects:
  • Humans
  • Vaccines
  • Vaccination
  • Cost-Benefit Analysis
  • Models, Economic
  • Centers for Disease Control and Prevention, U.S.
  • Health Care Costs
  • Adult
• Keywords:
  • United States
  • Vaccine cost
  • Cost-effectiveness analysis methods
• Source:
  Vaccine, 2025, v. 47
• DOI:
  https://doi.org/10.1016/j.vaccine.2024.126667
• ISSN:
  0264-410X ; 1873-2518
• Pubmed ID:
  39754832
• Pubmed Central ID:
  PMC11822687
• Document Type:
  Text
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Genre:
  Journal Article
• Place as Subject:
  United States
• Pages in Document:
  126667 (15 pdf pages)
• Volume:
  47
• Download URL:
  https://stacks.cdc.gov/view/cdc/261804/cdc_261804_DS1.pdf
• File Type:
  [PDF - 375.65 KB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:facba8be47be3f05268b6efa3aa7e7ee944f0cea3c3c5d581ebb7b2d54fc8310d161489647ca1d2280c5104b3dcef205d5d7a43aa34efb80222f5e699617b059