Paducah Gaseous Diffusion Plant mortality study: job title analysis.

Details

• Personal Author:
  Aldrich T ; Chan MC ; Hornung, Richard W. ; Hughes TS ; Muldoon SB ; Rice C ; Tollerud DJ
• Description:
  The Paducah Gaseous Diffusion Plant (PGDP) is currently the only operating uranium enrichment facility in the U.S, and the only one that has not undergone an assessment of worker mortality. It was commissioned in 1952 as part of a U.S. government program to produce enriched uranium to fuel military reactors and produce nuclear weapons. Demographic, work history and vital status data were collected on 6820 workers. A total of 1674 deaths were identified. The Life Table Analysis System (LTAS) was used to analyze outcomes based on job title. Standardized Mortality Ratios (SMRs) and Standardized Risk Ratios (SRRs) were calculated analyzing the cohort for 92 causes of death. Job titles at the plant were condensed into 44 grouped job titles based on similarity of task and exposures. Analyses were further limited to job titles with a minimum of 5% of the person years of the whole cohort, resulting in 11 job titles analyzed. Lymphatic and hematopoietic cancers have been associated with low-dose radiation exposure and were of a-priori interest. All causes and all cancers outcomes had significantly lower SMRs than the referent population, reflecting a strong healthy worker effect. Non-significant elevations were found for lymphatic and hematopoietic cancers for the job titles Chemical Operator, Maintenance, and Security. Security had a significant elevation in Non-Hodgkin's lymphoma. Office workers had a significant elevation in colon cancer. Elevations in deaths due to Alzheimer's disease were found to reach significance for the cohort and the job titles Laboratory and Maintenance. [Description provided by NIOSH]
• Subjects:
  Epidemiology Hematopoietic System Lymphatic System Morbidity Mortality Neoplasms Nuclear Power Plants Occupational Health Radiation Risk Assessment Risk Factors Safety Uranium Workplace

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• Keywords:
  Author Keywords: Occupational Exposure; Outcomes Research Uranium-compounds; Workers; Work-environment; Mortality-rates; Morbidity-rates; Nuclear-reactions; Nuclear-hazards; Nuclear-energy; Statistical-analysis; Epidemiology; Risk-factors; Exposure-limits; Exposure-levels; Cancer; Lymphatic-cancer; Lymphatic-system-disorders; Lymphatic-system; Hematopoietic-system; Radiation-contamination; Radiation-effects; Radiation-exposure; Radiation-hazards; Radiation-levels; Radiation-measurement; Radiation-properties; Radiation-sickness;
• Publisher:
  American Public Health Association
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Abstract or Summary
• Place as Subject:
  Kentucky ; Ohio ; OSHA Region 4 ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• NIOSHTIC Number:
  nn:20040412
• Citation:
  APHA 137th Annual Meeting and Exposition, November 7-11, 2009, Philadelphia, Pennsylvania. Washington, DC: American Public Health Association, 2009 Nov; :200086
• CAS Registry Number:
  Uranium (CAS RN 7440-61-1)
• Federal Fiscal Year:
  2010
• Performing Organization:
  University of Louisville
• Peer Reviewed:
  False
• Start Date:
  20050701
• Source Full Name:
  APHA 137th Annual Meeting and Exposition, November 7-11, 2009, Philadelphia, Pennsylvania
• End Date:
  20090630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7dc847c09aedf140bc731323e8446b4703641ae07d6ad9e7b7238120dab30b8f7dcaa9b938d34d035f87873a0fe7fec262d5d13dcaf290925445e82b6de3b57d
• Download URL:
  https://stacks.cdc.gov/view/cdc/248167/cdc_248167_DS1.pdf
• File Type:
  [PDF - 168.02 KB ]