Emergence of Unusual G6P Rotaviruses in Children, Burkina Faso, 2009–2010
Published Date:Apr 2012
Source:Emerg Infect Dis. 18(4):589-597.
Molecular Sequence Data
Multiplex Polymerase Chain Reaction
Sequence Analysis, DNA
Description:To obtain more information about rotavirus (ROTAV) genotypes in Burkina Faso, we characterized 100 ROTAVs isolated from fecal samples of children with acute gastroenteritis in the capital city of Ouagadougou, during December 2009-March 2010. Of note, 13% of the ROTAV-positive samples, including those with mixed infections, were positive for the unusual G6 genotype ROTAV strain. The genotypes identified were G9P, G6P, G1P, G3P, G1P, and G2P. G9P subgroup (SG)II strains dominated during the beginning of the ROTAV season, but later in the season, other G types associated with P and SGI specificity emerged. This emergence was related to a shift in the overall age of infected children; ROTAV SGII infected younger children and induced more severe symptoms. The finding of a high incidence of G6P strains highlights the need for long-term surveillance of ROTAV strains in Burkina Faso, especially when ROTAV vaccination is being considered in several African countries.
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