Emergence of Unusual G6P[6] Rotaviruses in Children, Burkina Faso, 2009–2010

Nordgren, Johan; Nitiema, Leon W.; Sharma, Sumit; Ouermi, Djeneba; Traore, Alfred S.; Simpore, Jacques; Svensson, Lennart

doi:10.3201/eid1804.110973

i

Emergence of Unusual G6P[6] Rotaviruses in Children, Burkina Faso, 2009–2010

Supporting Files Public Domain

Apr 2012
By Nordgren, Johan ; Nitiema, Leon W. ; Sharma, Sumit ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Nordgren, Johan ; Nitiema, Leon W. ; Sharma, Sumit ; Ouermi, Djeneba ; Traore, Alfred S. ; Simpore, Jacques ; Svensson, Lennart
Description:

To obtain more information about rotavirus (ROTAV) genotypes in Burkina Faso, we characterized 100 ROTAVs isolated from fecal samples of children with acute gastroenteritis in the capital city of Ouagadougou, during December 2009-March 2010. Of note, 13% of the ROTAV-positive samples, including those with mixed infections, were positive for the unusual G6 genotype ROTAV strain. The genotypes identified were G9P[8], G6P[6], G1P[6], G3P[6], G1P[8], and G2P[4]. G9P[8] subgroup (SG)II strains dominated during the beginning of the ROTAV season, but later in the season, other G types associated with P[6] and SGI specificity emerged. This emergence was related to a shift in the overall age of infected children; ROTAV SGII infected younger children and induced more severe symptoms. The finding of a high incidence of G6P[6] strains highlights the need for long-term surveillance of ROTAV strains in Burkina Faso, especially when ROTAV vaccination is being considered in several African countries.
Subjects:

Acute Gastroenteritis Base Sequence Child, Preschool Children Diarrhea Emergence G6P[6] Rotaviruses Gastroenteritis Genes, Viral Genotype Genotypes G Genotype Humans Incidence Models, Genetic Molecular Sequence Data Molecular Typing Multiplex Polymerase Chain Reaction P Genotype Phylogeny Reference Standards Research Rotavirus Rotavirus Infections Sequence Analysis, DNA Surveillance Viruses
Source:

Emerg Infect Dis. 18(4):589-597.
Document Type:

Journal Article
Place as Subject:

Burkina Faso
Location:

Africa
Volume:

18
Issue:

4
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:0bd5f126fa4e2350a8168a9409a15ab6e4533d89bda14013c2f7a73d1b4e83e6
Download URL:

https://stacks.cdc.gov/view/cdc/23863/cdc_23863_DS1.pdf
File Type:

[PDF - 317.90 KB ]

File Language:

English

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