Influenza B Viruses with Mutation in the Neuraminidase Active Site, North Carolina, USA, 2010–11
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Public Domain
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Nov 2011
Details
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Alternative Title:Emerg Infect Dis
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Personal Author:
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Description:Oseltamivir is 1 of 2 antiviral medications available for the treatment of influenza B virus infections. We describe and characterize a cluster of influenza B viruses circulating in North Carolina with a mutation in the neuraminidase active site that may reduce susceptibility to oseltamivir and the investigational drug peramivir but not to zanamivir.
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Subjects:
- Dispatch
- Adolescent
- Adult
- Antiviral Agents
- Catalytic Domain
- Child
- Child, Preschool
- Cyclopentanes
- Drug Resistance, Viral
- Guanidines
- Hemagglutinin Glycoproteins, Influenza Virus
- Humans
- Infant
- Influenza B virus
- Influenza, Human
- Microbial Sensitivity Tests
- Middle Aged
- Mutation
- Neuraminidase
- Oseltamivir
- Phylogeny
- Polymorphism, Single Nucleotide
- Young Adult
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Source:Emerg Infect Dis. 17(11):2043-2046.
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Document Type:
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Location:
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Volume:17
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Issue:11
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Download URL:
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Main Document Checksum:urn:sha256:496c78daed820391da3a2c8b2bcde5d18bc135b946d93a2a914192d52cc00716
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Emerging Infectious Diseases