Influenza B Viruses with Mutation in the Neuraminidase Active Site, North Carolina, USA, 2010–11

Sleeman, Katrina; Sheu, Tiffany G.; Moore, Zack; Kilpatrick, Susan; Garg, Shikha; Fry, Alicia M.; Gubareva, Larisa V.

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CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners. As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.

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Influenza B Viruses with Mutation in the Neuraminidase Active Site, North Carolina, USA, 2010–11

Nov 2011
By Sleeman, Katrina ; Sheu, Tiffany G. ; Moore, Zack ; ...
Source: Emerg Infect Dis. 17(11):2043-2046.

[PDF-303.27 KB]

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Sleeman, Katrina ; Sheu, Tiffany G. ; Moore, Zack ; Kilpatrick, Susan ; Garg, Shikha ; ... More +

Sleeman, Katrina ; Sheu, Tiffany G. ; Moore, Zack ; Kilpatrick, Susan ; Garg, Shikha ; Fry, Alicia M. ; Gubareva, Larisa V. Less -
Description:

Oseltamivir is 1 of 2 antiviral medications available for the treatment of influenza B virus infections. We describe and characterize a cluster of influenza B viruses circulating in North Carolina with a mutation in the neuraminidase active site that may reduce susceptibility to oseltamivir and the investigational drug peramivir but not to zanamivir.
Subjects:

[+]

Adolescent Adult Antiviral Agents Catalytic Domain Child Child, Preschool Cyclopentanes Dispatch Drug Resistance, Viral Guanidines Hemagglutinin Glycoproteins, Influenza Virus Humans Infant Influenza, Human Influenza B Virus Microbial Sensitivity Tests Middle Aged Mutation Neuraminidase Oseltamivir Phylogeny Polymorphism, Single Nucleotide Young Adult
Source:

Emerg Infect Dis. 17(11):2043-2046.
Document Type:

Journal Article
Place as Subject:

North Carolina
Location:

North America
Volume:

17
Issue:

11
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:496c78daed820391da3a2c8b2bcde5d18bc135b946d93a2a914192d52cc00716
Download URL:

https://stacks.cdc.gov/view/cdc/23735/cdc_23735_DS1.pdf
File Type:

	11-0787-F.gif	gif
	11-0787-F.jpg	jpeg
	11-0787_finalD.nxml	txt
	license.txt	txt

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