Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Sleeman, Katrina ; Sheu, Tiffany G. ; Moore, Zack ; Kilpatrick, Susan ; Garg, Shikha ; ... More +
Sleeman, Katrina ; Sheu, Tiffany G. ; Moore, Zack ; Kilpatrick, Susan ; Garg, Shikha ; Fry, Alicia M. ; Gubareva, Larisa V. Less -
Description:
Oseltamivir is 1 of 2 antiviral medications available for the treatment of influenza B virus infections. We describe and characterize a cluster of influenza B viruses circulating in North Carolina with a mutation in the neuraminidase active site that may reduce susceptibility to oseltamivir and the investigational drug peramivir but not to zanamivir.
Subjects:
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Adolescent Adult Antiviral Agents Catalytic Domain Child Child, Preschool Cyclopentanes Dispatch Drug Resistance, Viral Guanidines Hemagglutinin Glycoproteins, Influenza Virus Humans Infant Influenza, Human Influenza B Virus Microbial Sensitivity Tests Middle Aged Mutation Neuraminidase Oseltamivir Phylogeny Polymorphism, Single Nucleotide Young Adult
Source:
Emerg Infect Dis. 17(11):2043-2046.
Document Type:
Journal Article
Place as Subject:
North Carolina
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:496c78daed820391da3a2c8b2bcde5d18bc135b946d93a2a914192d52cc00716
Download URL:
https://stacks.cdc.gov/view/cdc/23735/cdc_23735_DS1.pdf
File Type:

Supporting Files

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  	11-0787_finalD.nxml	txt
  	license.txt	txt

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