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Sequential Gastroenteritis Episodes Caused by 2 Norovirus Genotypes
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  • Alternative Title:
    Emerg Infect Dis
  • Description:
    We investigated sequential episodes of acute norovirus gastroenteritis in a young child within an 11-month period. The infections were caused by 2 distinct genotypes (GII.4 and GII.6). Failure to achieve cross-protective immunity was linked to absence of an enduring and cross-reactive mucosal immune response, a critical consideration for vaccine design.

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