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Sequential Gastroenteritis Episodes Caused by 2 Norovirus Genotypes
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Published Date:
Jun 2014
Publisher's site:Source:Emerg Infect Dis. 20(6):1016-1018.
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Alternative Title:Emerg Infect Dis
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Description:We investigated sequential episodes of acute norovirus gastroenteritis in a young child within an 11-month period. The infections were caused by 2 distinct genotypes (GII.4 and GII.6). Failure to achieve cross-protective immunity was linked to absence of an enduring and cross-reactive mucosal immune response, a critical consideration for vaccine design.
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