Does Air Pollution Accelerate Progression of Atherosclerosis?

Details

• Personal Author:
  Kaufman JD
• Description:
  It is an accepted biological premise that development of clinical cardiovascular disease is the result of gene-environment interactions: gene expression that leads to disease is the result of environmental influences in the setting of a susceptible genetic framework. Intensive efforts have gone into exploring the nature of the genetic susceptibility. Meanwhile, investigations of the "environmental" factors underlying cardiovascular diseases have principally focused on factors that are modifiable at the individual level, such as diet, exercise patterns, and medications. However, emerging published data now support the notion that another set of environmental factors-including air pollution, over which individuals have less control-are also influential in the development of clinically important cardiovascular disease. Work published in the current issue of the Journaland recently appearing in other venues highlights the potential role of ambient air pollution exposures in the development of atherosclerotic disease. [Description provided by NIOSH]
• Subjects:
  Air Pollution Cardiovascular Diseases Cardiovascular System Occupational Health Safety
• Keywords:
  Air Pollution Author Keywords: Air Pollution Cardiovascular Disease Carotid Intima-media Thickness Environmental Health Genetic Factors Health Effects Particulate Matter Subclinical Atherosclerosis Traffic
• ISSN:
  0735-1097
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 10 ; Washington
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  56
• Issue:
  22
• NIOSHTIC Number:
  nn:20054876
• Citation:
  J Am Coll Cardiol 2010 Nov; 56(22):1809-1811
• Contact Point Address:
  Dr. Joel D. Kaufman, Departments of Medicine, Environmental and Occupational Health Sciences, and Epidemiology, University of Washington, 4225 Roosevelt Way NE, Suite 100, Seattle, Washington 98105-6099
• Email:
  joelk@uw.edu
• Federal Fiscal Year:
  2011
• Performing Organization:
  University of Washington
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  Journal of the American College of Cardiology
• End Date:
  20250630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:83d4e1d0ac7d0957a286a0993e93e1f76494d8b1af23f6c5a34c7715742d1a60c083b593134212e0ddb7534bf6f6aaaf72c47cdbf55fec821dad5500c04efbe2
• Download URL:
  https://stacks.cdc.gov/view/cdc/217290/cdc_217290_DS1.pdf
• File Type:
  [PDF - 68.55 KB ]