Increased Incidence of Invasive Fusariosis with Cutaneous Portal of Entry, Brazil

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Nucci, Marcio ; Varon, Andrea G. ; Garnica, Marcia ; Akiti, Tiyomi ; Barreiros, Gloria ; Trope, Beatriz Moritz ; Nouér, Simone A.
• Description:
  Invasive fusariosis (IF) is an infection with Fusarium spp. fungi that primarily affects patients with hematologic malignancies and hematopoietic cell transplant recipients. A cutaneous portal of entry is occasionally reported. We reviewed all cases of IF in Brazil during 2000-2010, divided into 2 periods: 2000-2005 (period 1) and 2006-2010 (period 2). We calculated incidence rates of IF and of superficial infections with Fusarium spp. fungi identified in patients at a dermatology outpatient unit. IF incidence for periods 1 and 2 was 0.86 cases versus 10.23 cases per 1,000 admissions (p<0.001), respectively; superficial fusarial infection incidence was 7.23 versus 16.26 positive cultures per 1,000 superficial cultures (p<0.001), respectively. Of 21 cases of IF, 14 showed a primary cutaneous portal of entry. Further studies are needed to identify reservoirs of these fungi in the community and to implement preventive measures for patients at risk.
• Subjects:
  Dermatomycoses Fusariosis Fusarium Humans Immunocompromised Host Incidence Leukemia, Myeloid, Acute
• Source:
  Emerg Infect Dis. 19(10):1567-1572.
• Document Type:
  Journal Article
• Genre:
  CME
• Place as Subject:
  Brazil
• Volume:
  19
• Issue:
  10
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:e78be631a3a4f494680680747584de981c33029b305cb8230ace326cc8a77112
• Download URL:
  https://stacks.cdc.gov/view/cdc/20914/cdc_20914_DS1.pdf
• File Type:
  [PDF - 561.07 KB ]