Evaluation of 9-methylaminomethylanthracene as a chemical label for total reactive isocyanate group: a comparison of mono- and di- isocyanate monomers

Details

• Personal Author:
  Esmundo FR ; Lefante JJ ; Poovey HG ; Rando RJ
• Description:
  The consistency of response by ultraviolet (UV) and fluorescence detection in a series of urea derivatives prepared from 9- methylamino-methylanthracene (73356191) (MAMA) and 11 isocyanate compounds was evaluated. Aliphatic, aromatic, mono-isocyanates and diisocyanates were included to determine possible structure and response relationships. The authors conclude that the use of MAMA as a derivatizing agent, along with analysis by high pressure liquid chromatography with UV absorbance and fluorescence detection offered a promising approach to the identification and quantitation of airborne total reactive isocyanate group. The UV absorbing properties of a series of MAMA derivatives was remarkably consistent and primarily dependent on the number of MAMA units in the resulting compound. The fluorescence response was quite variable and correlated in large part with structural properties. [Description provided by NIOSH]
• Subjects:
  Amines Chemistry Chemistry, Analytic Chromatography Coloring Agents Cyanides Occupational Health Safety
• Keywords:
  Analytical-chemistry Analytical-methods Chemical-analysis Chromatographic-analysis Cyanide-compounds Dyeing-industry Grants-other Industrial-hygiene NIOSH-Grant NIOSH-Publication
• ISSN:
  0148-3919
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Louisiana ; OSHA Region 6
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  16
• Issue:
  18
• NIOSHTIC Number:
  nn:00218717
• Citation:
  J Liq Chromatogr 1993 Dec; 16(18):3977-3996
• Contact Point Address:
  Medicine Tulane University 1700 Perdido St New Orleans, LA 70112
• CAS Registry Number:
  9-Anthracenemethanamine, N-methyl- (CAS RN 73356-19-1)
• Federal Fiscal Year:
  1994
• NORA Priority Area:
  Grants Other
• Performing Organization:
  Tulane University of Louisiana, New Orleans, Louisiana
• Peer Reviewed:
  True
• Start Date:
  19890701
• Source Full Name:
  Journal of Liquid Chromatography
• End Date:
  19990331
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:b6b9b99c98918cd0b685adc77fadd18733585fa9b786b27292860333a0550f088e0ff1754e100b751aabee7b70bc6b97aae5a91fae511544364f86c42c6e95e3
• Download URL:
  https://stacks.cdc.gov/view/cdc/204659/cdc_204659_DS1.pdf
• File Type:
  [PDF - 910.32 KB ]