Nanomaterial Labels in Electrochemical Immunosensors and Immunoassays

Details

• Personal Author:
  Lin Y ; Liu G
• Description:
  This article reviews recent advances in nanomaterial labels in electrochemical immunosensors and immunoassays. Various nanomaterial labels are discussed, including colloidal gold/silver, semiconductor nanoparticles, and markers loaded nanocarriers (carbon nanotubes, apoferritin, silica nanoparticles, and liposome beads). The enormous signal enhancement associated with the use of nanomaterial labels and with the formation of nanomaterial-antibody-antigen assemblies provides the basis for ultrasensitive electrochemical detection of disease-related protein biomarkers, biothreat agents, or infectious agents. In general, all endeavors cited here are geared to achieve one or more of the following goals: signal amplification by several orders of magnitude, lower detection limits, and detecting multiple targets. [Description provided by NIOSH]
• Subjects:
  Biological Factors Biological Products Biomarkers Immune System Occupational Health Particulate Matter Safety
• Keywords:
  Author Keywords: Nanomaterials Biological-agents Biological-effects Biological-factors Biological-function Biological-monitoring Biological-systems Carbon Nanotubes Electrochemical-properties Electrochemical-reactions Electrochemistry Immune-reaction Immunoassays Immunochemistry Immunosensors Nanoparticles Nanotechnology Particle-counters Particulate-sampling-methods Particulates

  More +
• ISSN:
  0039-9140
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  North Dakota ; OSHA Region 10 ; OSHA Region 8 ; Washington
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  308-317
• Volume:
  74
• Issue:
  3
• NIOSHTIC Number:
  nn:20034119
• Citation:
  Talanta 2007 Dec; 74(3):308-317
• Contact Point Address:
  Guodong Liu, Department of Chemistry and Molecular Biology, North Dakota State University, Fargo, ND 58105-5516
• Email:
  guodong.liu@ndsu.edu
• CAS Registry Number:
  Carbon (CAS RN 7440-44-0)
• Federal Fiscal Year:
  2008
• NORA Priority Area:
  Agriculture, Forestry and Fishing
• Performing Organization:
  Battelle Pacific Northwest Laboratories
• Peer Reviewed:
  True
• Start Date:
  20060901
• Source Full Name:
  Talanta
• End Date:
  20170831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:903e0dd63391a4b55c0230169fa9fec2af8ef0ba5f3c1ee4f940cd30f6a25caba2e7f8b0ad0c906b6f10f9982db0cc5c0dd8dbaefd313493612a903406015d28
• Download URL:
  https://stacks.cdc.gov/view/cdc/189485/cdc_189485_DS1.pdf
• File Type:
  [PDF - 1.01 MB ]