Active Tuberculosis among Homeless Persons, Toronto, Ontario, Canada, 1998–2007

Khan, Kamran; Rea, Elizabeth; McDermaid, Cameron; Stuart, Rebecca; Chambers, Catharine; Wang, Jun; Chan, Angie; Gardam, Michael; Jamieson, Frances; Yang, Jae; Hwang, Stephen W.

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Active Tuberculosis among Homeless Persons, Toronto, Ontario, Canada, 1998–2007

Published Date:

Mar 2011

Source:

Emerg Infect Dis. 17(3):357-365.

[PDF-327.19 KB]

Details:

Alternative Title:

Emerg Infect Dis

Personal Author:

Khan, Kamran ; Rea, Elizabeth ; McDermaid, Cameron ; Stuart, Rebecca ; Chambers, Catharine ; ... More ▼

Description:

While tuberculosis (TB) in Canadian cities is increasingly affecting foreign-born persons, homeless persons remain at high risk. To assess trends in TB, we studied all homeless persons in Toronto who had a diagnosis of active TB during 1998-2007. We compared Canada-born and foreign-born homeless persons and assessed changes over time. We identified 91 homeless persons with active TB; they typically had highly contagious, advanced disease, and 19% died within 12 months of diagnosis. The proportion of homeless persons who were foreign-born increased from 24% in 1998-2002 to 39% in 2003-2007. Among foreign-born homeless persons with TB, 56% of infections were caused by strains not known to circulate among homeless persons in Toronto. Only 2% of infections were resistant to first-line TB medications. The rise in foreign-born homeless persons with TB strains likely acquired overseas suggests that the risk for drug-resistant strains entering the homeless shelter system may be escalating.

Subject:

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Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

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