Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Inoue, Masafumi ; Barkham, Timothy ; Leo, Yee-Sin ; Chan, Kwai-Peng ; Chow, Angela ; ... More +
Inoue, Masafumi ; Barkham, Timothy ; Leo, Yee-Sin ; Chan, Kwai-Peng ; Chow, Angela ; Wong, Christopher W. ; Lee, Raphael Tze-Chuen ; Maurer-Stroh, Sebastian ; Lin, Raymond ; Lin, Cui Less -
Description:
An oseltamivir-resistant influenza A pandemic (H1N1) 2009 virus evolved and emerged from zero to 52% of detectable virus within 48 hours of a patient's exposure to oseltamivir. Phylogenetic analysis and data gathered by pyrosequencing and cloning directly on clinical samples suggest that the mutant emerged de novo.
Subjects:
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Adult Antiviral Agents Drug Resistance, Viral Evolution, Molecular Female Humans Influenza, Human Influenza A Virus, H1N1 Subtype Mutation Oseltamivir Pandemics Phylogeny Sequence Analysis, Dna Time Factors
Source:
Emerg Infect Dis. 16(10):1633-1636.
Document Type:
Journal Article
Place as Subject:
Singapore
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:fcb505f168ab4c67f5128c760c6636bdf5b07936ebe73b370946394e50f78653
Download URL:
https://stacks.cdc.gov/view/cdc/18351/cdc_18351_DS1.pdf
File Type:

Supporting Files

• 	10-0688-F.gif	gif
  	10-0688-F.jpg	jpeg
  	10-0688-Techapp_6p.pdf	pdf
  	10-0688_finalD.nxml	txt
  	license.txt	txt

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