Transfer of Carbapenem-Resistant Plasmid from Klebsiella pneumoniae ST258 to Escherichia coli in Patient

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Goren, Moran G. ; Carmeli, Yehuda ; Schwaber, Mitchell J. ; Chmelnitsky, Inna ; Schechner, Vered ; Navon-Venezia, Shiri
• Description:
  Klebsiella pneumoniae carbapenemase (KPC) 3-producing Escherichia coli was isolated from a carrier of KPC-3-producing K. pneumoniae. The KPC-3 plasmid was identical in isolates of both species. The patient's gut flora contained a carbapenem-susceptible E. coli strain isogenic with the KPC-3-producing isolate, which suggests horizontal interspecies plasmid transfer.
• Subjects:
  Aged, 80 And Over Anti-Bacterial Agents Antibiotic Resistance Bacteria Bacterial Proteins Beta-Lactamases Beta-Lactams Carbapenem-resistant Plasmid Colistin Conjugation, Genetic Dispatch Drug Resistance, Bacterial Drug Therapy, Combination Escherichia Coli Escherichia Coli Infections Gastrointestinal Tract Horizontal Gene Transfer Humans Israel Klebsiella Infections Klebsiella Pneumoniae KPC Male Metronidazole Plasmids Vancomycin

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• Source:
  Emerg Infect Dis. 16(6):1014-1017.
• Document Type:
  Journal Article
• Volume:
  16
• Issue:
  6
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:1c2a59c315102d05cc41cb0074c4fff648e27c16b34c7adcada78d29d5dd70f5
• Download URL:
  https://stacks.cdc.gov/view/cdc/18146/cdc_18146_DS1.pdf
• File Type:
  [PDF - 458.93 KB ]