Experimental Infection of Squirrel Monkeys with Nipah Virus

Marianneau, Philippe; Guillaume, Vanessa; Wong, K. Thong; Badmanathan, Munisamy; Looi, Ren Yih; Murri, Séverine; Loth, Philippe; Tordo, Noël; Wild, T. Fabian; Horvat, Branka; Contamin, Hugues

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Experimental Infection of Squirrel Monkeys with Nipah Virus

Published Date:

Mar 2010

Source:

Emerg Infect Dis. 16(3):507-510.

[PDF - 302.41 KB]

Details:

Personal Authors:

Marianneau, Philippe ; Guillaume, Vanessa ; Wong, K. Thong ; Badmanathan, Munisamy ; Looi, Ren Yih ; ... More ▼

Keywords:

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Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

Description:

We infected squirrel monkeys (Saimiri sciureus) with Nipah virus to determine the monkeys' suitability for use as primate models in preclinical testing of preventive and therapeutic treatments. Infection of squirrel monkeys through intravenous injection was followed by high death rates associated with acute neurologic and respiratory illness and viral RNA and antigen production.

Supporting Files:

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