Experimental Infection of Squirrel Monkeys with Nipah Virus

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Marianneau, Philippe ; Guillaume, Vanessa ; Wong, K. Thong ; Badmanathan, Munisamy ; Looi, Ren Yih ; Murri, Séverine ; Loth, Philippe ; Tordo, Noël ; Wild, T. Fabian ; Horvat, Branka ; Contamin, Hugues
• Description:
  We infected squirrel monkeys (Saimiri sciureus) with Nipah virus to determine the monkeys' suitability for use as primate models in preclinical testing of preventive and therapeutic treatments. Infection of squirrel monkeys through intravenous injection was followed by high death rates associated with acute neurologic and respiratory illness and viral RNA and antigen production.
• Subjects:
  Animals Antibodies, Viral Antigens, Viral Disease Models, Animal Dispatch ELISA Emergent Infection Encephalitis Henipavirus Infections Humans Immunohistology Nipah Virus Pathogenesis Primates RNA, Viral RT-PCR Saimiri Saimiri Sciureus Squirrel Monkey Viruses Zoonoses

  More +
• Source:
  Emerg Infect Dis. 16(3):507-510.
• Document Type:
  Journal Article
• Volume:
  16
• Issue:
  3
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:7266dd758d03a561aa39722b9460087aa6c3ff3b2b4e5ec8a92dcfc8cd010e04
• Download URL:
  https://stacks.cdc.gov/view/cdc/18086/cdc_18086_DS1.pdf
• File Type:
  [PDF - 302.41 KB ]