Experimental Infection of Squirrel Monkeys with Nipah Virus

Marianneau, Philippe; Guillaume, Vanessa; Wong, K. Thong; Badmanathan, Munisamy; Looi, Ren Yih; Murri, Séverine; Loth, Philippe; Tordo, Noël; Wild, T. Fabian; Horvat, Branka; Contamin, Hugues

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Experimental Infection of Squirrel Monkeys with Nipah Virus

Mar 2010
By Marianneau, Philippe ; Guillaume, Vanessa ; Wong, K. Thong ; ...
Source: Emerg Infect Dis. 16(3):507-510.

[PDF-302.41 KB]

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Marianneau, Philippe ; Guillaume, Vanessa ; Wong, K. Thong ; Badmanathan, Munisamy ; Looi, Ren Yih ; ... More +

Marianneau, Philippe ; Guillaume, Vanessa ; Wong, K. Thong ; Badmanathan, Munisamy ; Looi, Ren Yih ; Murri, Séverine ; Loth, Philippe ; Tordo, Noël ; Wild, T. Fabian ; Horvat, Branka ; Contamin, Hugues Less -
Description:

We infected squirrel monkeys (Saimiri sciureus) with Nipah virus to determine the monkeys' suitability for use as primate models in preclinical testing of preventive and therapeutic treatments. Infection of squirrel monkeys through intravenous injection was followed by high death rates associated with acute neurologic and respiratory illness and viral RNA and antigen production.
Subjects:

[+]

Animals Antibodies, Viral Antigens, Viral Disease Models, Animal Dispatch ELISA Emergent Infection Encephalitis Henipavirus Infections Humans Immunohistology Nipah Virus Pathogenesis Primates RNA, Viral RT-PCR Saimiri Saimiri Sciureus Squirrel Monkey Viruses Zoonoses
Source:

Emerg Infect Dis. 16(3):507-510.
Document Type:

Journal Article
Volume:

16
Issue:

3
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:7266dd758d03a561aa39722b9460087aa6c3ff3b2b4e5ec8a92dcfc8cd010e04
Download URL:

https://stacks.cdc.gov/view/cdc/18086/cdc_18086_DS1.pdf
File Type:

	09-1346-F.gif	gif
	09-1346-F.jpg	jpeg
	09-1346_finalD.nxml	txt
	license.txt	txt

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