Alterations in Blood Chemistry Levels Associated With Nipah Virus Disease in the Syrian Hamster Model

Genzer, Sarah C.; Welch, Stephen R.; Scholte, Florine E.M.; Harmon, Jessica R.; Coleman-McCray, JoAnn D.; Lo, Michael K.; Montgomery, Joel M.; Nichol, Stuart T.; Spiropoulou, Christina F.; Spengler, Jessica R.

doi:10.1093/infdis/jiz552

Advanced Search

Select up to three search categories and corresponding keywords using the fields to the right. Refer to the Help section for more detailed instructions.

Search our Collections & Repository

Advanced Search
Custom Query

All these words:

For very narrow results

This exact word or phrase:

When looking for a specific result

Any of these words:

Best used for discovery & interchangable words

None of these words:

Recommended to be used in conjunction with other fields

Language:

Dates

Publication Date Range:

to

Document Data

Title:

Document Type:

Library

Collection:

Series:

People

Author:

Clear All

Query Builder

Query box

Clear All

For additional assistance using the Custom Query please check out our Help Page

i

Alterations in Blood Chemistry Levels Associated With Nipah Virus Disease in the Syrian Hamster Model

5 01 2020
By Genzer, Sarah C. ; Welch, Stephen R. ; Scholte, Florine E.M. ; ...
http://dx.doi.org/10.1093/infdis/jiz552
Source: J Infect Dis. 221(Suppl 4):S454-S459

[PDF-233.47 KB]

English

Details Supporting Files You May Also Like

Details:

Alternative Title:

J Infect Dis
Personal Author:

Genzer, Sarah C. ; Welch, Stephen R. ; Scholte, Florine E.M. ; Harmon, Jessica R. ; Coleman-McCray, JoAnn D. ; ... More +

Genzer, Sarah C. ; Welch, Stephen R. ; Scholte, Florine E.M. ; Harmon, Jessica R. ; Coleman-McCray, JoAnn D. ; Lo, Michael K. ; Montgomery, Joel M. ; Nichol, Stuart T. ; Spiropoulou, Christina F. ; Spengler, Jessica R. Less -
Description:

Nipah virus (NiV; family Paramyxoviridae, genus Henipavirus) infection can cause severe respiratory and neurological disease in humans. The pathophysiology of disease is not fully understood, and it may vary by presentation and clinical course. In this study, we investigate changes in blood chemistry in NiV-infected Syrian hamsters that survived or succumbed to disease. Increased sodium and magnesium and decreased albumin and lactate levels were detected in animals euthanized with severe clinical disease compared with mock-infected controls. When subjects were grouped by clinical syndrome, additional trends were discernable, highlighting changes associated with either respiratory or neurological disease.
Subjects:

[+]

Alanine Transaminase Animals Article Blood Cricetinae Henipavirus Infections Lactic Acid Magnesium Mesocricetus Neurological Nipah Virus Respiratory Serum Albumin Sodium Syrian Hamster
Source:

J Infect Dis. 221(Suppl 4):S454-S459
Pubmed ID:

31747016
Pubmed Central ID:

PMC7368165
Document Type:

Journal Article
Funding:

CC999999/ImCDC/Intramural CDC HHSUnited States/ ; R01 AI109008/AI/NIAID NIH HHSUnited States/

CC999999/ImCDC/Intramural CDC HHSUnited States/ ; R01 AI109008/AI/NIAID NIH HHSUnited States/ Less -
Collection(s):

CDC Public Access
Main Document Checksum:

[+]

urn:sha256:49a6ab25dcb6246f70c6c9b935314299f408a0aa1e7c82461dcbc6b2b147bdad
Download URL:

https://stacks.cdc.gov/view/cdc/110544/cdc_110544_DS1.pdf
File Type:

	nihms-1600476-f0001.gif	gif
	nihms-1600476-f0001.jpg	jpeg
	nihms-1600476-f0002.gif	gif
	nihms-1600476-f0002.jpg	jpeg
	nihms-1600476.nxml	xml
	NIHMS1600476-supplement-1.pdf	pdf

More +