Rare Influenza A (H3N2) Variants with Reduced Sensitivity to Antiviral Drugs

Dapat, Clyde; Suzuki, Yasushi; Saito, Reiko; Kyaw, Yadanar; Myint, Yi Yi; Lin, Nay; Oo, Htun Naing; Oo, Khin Yi; Win, Ne; Naito, Makoto; Hasegawa, Go; Dapat, Isolde C.; Zaraket, Hassan; Baranovich, Tatiana; Nishikawa, Makoto; Saito, Takehiko; Suzuki, Hiroshi

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Rare Influenza A (H3N2) Variants with Reduced Sensitivity to Antiviral Drugs

Mar 2010
By Dapat, Clyde ; Suzuki, Yasushi ; Saito, Reiko ; ...
Source: Emerg Infect Dis. 16(3):493-496.

[PDF-199.60 KB]

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Dapat, Clyde ; Suzuki, Yasushi ; Saito, Reiko ; Kyaw, Yadanar ; Myint, Yi Yi ; ... More +

Dapat, Clyde ; Suzuki, Yasushi ; Saito, Reiko ; Kyaw, Yadanar ; Myint, Yi Yi ; Lin, Nay ; Oo, Htun Naing ; Oo, Khin Yi ; Win, Ne ; Naito, Makoto ; Hasegawa, Go ; Dapat, Isolde C. ; Zaraket, Hassan ; Baranovich, Tatiana ; Nishikawa, Makoto ; Saito, Takehiko ; Suzuki, Hiroshi Less -
Description:

In 2007 and 2008 in Myanmar, we detected influenza viruses A (H3N2) that exhibited reduced sensitivity to both zanamivir and amantadine. These rare and naturally occurring viruses harbored a novel Q136K mutation in neuraminidase and S31N mutation in M2.
Subjects:

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Amantadine Antiviral Agents Antiviral Drug Resistance Dispatch Drug Resistance, Viral Expedited H3N2 Subtype Humans Influenza, Human Influenza A Virus Influenza A Virus, H3N2 Subtype Microbial Sensitivity Tests Molecular Sequence Data Mutation Neuraminidase Phylogeny Sequence Analysis, DNA Viral Matrix Proteins Viral Proteins Viruses Zanamivir
Source:

Emerg Infect Dis. 16(3):493-496.
Document Type:

Journal Article
Place as Subject:

Myanmar
Location:

Asia
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:b79f2ae31be271eeb836456ceb0477866db99ee8de9e6060520cb24b3c321e63
Download URL:

https://stacks.cdc.gov/view/cdc/18080/cdc_18080_DS1.pdf
File Type:

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