Rare Influenza A (H3N2) Variants with Reduced Sensitivity to Antiviral Drugs

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Dapat, Clyde ; Suzuki, Yasushi ; Saito, Reiko ; Kyaw, Yadanar ; Myint, Yi Yi ; Lin, Nay ; Oo, Htun Naing ; Oo, Khin Yi ; Win, Ne ; Naito, Makoto ; Hasegawa, Go ; Dapat, Isolde C. ; Zaraket, Hassan ; Baranovich, Tatiana ; Nishikawa, Makoto ; Saito, Takehiko ; Suzuki, Hiroshi
• Description:
  In 2007 and 2008 in Myanmar, we detected influenza viruses A (H3N2) that exhibited reduced sensitivity to both zanamivir and amantadine. These rare and naturally occurring viruses harbored a novel Q136K mutation in neuraminidase and S31N mutation in M2.
• Subjects:
  Amantadine Antiviral Agents Antiviral Drug Resistance Dispatch Drug Resistance, Viral Expedited H3N2 Subtype Humans Influenza, Human Influenza A Virus Influenza A Virus, H3N2 Subtype Microbial Sensitivity Tests Molecular Sequence Data Mutation Neuraminidase Phylogeny Sequence Analysis, DNA Viral Matrix Proteins Viral Proteins Viruses Zanamivir

  More +
• Source:
  Emerg Infect Dis. 16(3):493-496.
• Document Type:
  Journal Article
• Place as Subject:
  Myanmar
• Location:
  Asia
• Volume:
  16
• Issue:
  3
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:b79f2ae31be271eeb836456ceb0477866db99ee8de9e6060520cb24b3c321e63
• Download URL:
  https://stacks.cdc.gov/view/cdc/18080/cdc_18080_DS1.pdf
• File Type:
  [PDF - 199.60 KB ]