Rare Influenza A (H3N2) Variants with Reduced Sensitivity to Antiviral Drugs
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Public Domain
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Mar 2010
Details
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Alternative Title:Emerg Infect Dis
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Personal Author:Dapat, Clyde ; Suzuki, Yasushi ; Saito, Reiko ; Kyaw, Yadanar ; Myint, Yi Yi ; Lin, Nay ; Oo, Htun Naing ; Oo, Khin Yi ; Win, Ne ; Naito, Makoto ; Hasegawa, Go ; Dapat, Isolde C. ; Zaraket, Hassan ; Baranovich, Tatiana ; Nishikawa, Makoto ; Saito, Takehiko ; Suzuki, Hiroshi
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Description:In 2007 and 2008 in Myanmar, we detected influenza viruses A (H3N2) that exhibited reduced sensitivity to both zanamivir and amantadine. These rare and naturally occurring viruses harbored a novel Q136K mutation in neuraminidase and S31N mutation in M2.
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Subjects:
- Dispatch
- Influenza A virus
- H3N2 subtype
- zanamivir
- amantadine
- antiviral drug resistance
- viruses
- expedited
- dispatch
- Amantadine
- Antiviral Agents
- Drug Resistance, Viral
- Humans
- Influenza A Virus, H3N2 Subtype
- Influenza, Human
- Microbial Sensitivity Tests
- Molecular Sequence Data
- Mutation
- Neuraminidase
- Phylogeny
- Sequence Analysis, DNA
- Viral Matrix Proteins
- Viral Proteins
- Zanamivir
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Source:Emerg Infect Dis. 16(3):493-496.
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Document Type:
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Place as Subject:
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Location:
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Volume:16
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Issue:3
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Download URL:
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Collection(s):
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Main Document Checksum:urn:sha256:b79f2ae31be271eeb836456ceb0477866db99ee8de9e6060520cb24b3c321e63
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