Macrolide-Resistant Shigella sonnei
Published Date:Aug 2008
Source:Emerg Infect Dis. 14(8):1297-1299.
Drug Resistance, Multiple, Bacterial
Electrophoresis, Gel, Pulsed-Field
Polymerase Chain Reaction
Description:Shigella sonnei UCN59, isolated during an outbreak of S. sonnei in January 2007, was resistant to azithromycin (MIC 64 mg/L). The isolate contained a plasmid-borne mph(A) gene encoding a macrolide 2 -phosphotransferase that inactivates macrolides. Emergence of the mph(A) gene in S. sonnei may limit usefulness of azithromycin for treatment of shigellosis.
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