Macrolide-Resistant Shigella sonnei

Boumghar-Bourtchai, Leyla; Mariani-Kurkdjian, Patricia; Bingen, Edouard; Filliol, Ingrid; Dhalluin, Anne; Ifrane, Shadia Ait; Weill, François-Xavier; Leclercq, Roland

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Macrolide-Resistant Shigella sonnei

Published Date:

Aug 2008

Source:

Emerg Infect Dis. 14(8):1297-1299.

[PDF - 193.20 KB]

Details:

Personal Authors:

Boumghar-Bourtchai, Leyla ; Mariani-Kurkdjian, Patricia ; Bingen, Edouard ; Filliol, Ingrid ; Dhalluin, Anne ; ... More ▼

Keywords:

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Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

Description:

Shigella sonnei UCN59, isolated during an outbreak of S. sonnei in January 2007, was resistant to azithromycin (MIC 64 mg/L). The isolate contained a plasmid-borne mph(A) gene encoding a macrolide 2 -phosphotransferase that inactivates macrolides. Emergence of the mph(A) gene in S. sonnei may limit usefulness of azithromycin for treatment of shigellosis.

Supporting Files:

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