Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Boumghar-Bourtchai, Leyla ; Mariani-Kurkdjian, Patricia ; Bingen, Edouard ; Filliol, Ingrid ; Dhalluin, Anne ; ... More +
Boumghar-Bourtchai, Leyla ; Mariani-Kurkdjian, Patricia ; Bingen, Edouard ; Filliol, Ingrid ; Dhalluin, Anne ; Ifrane, Shadia Ait ; Weill, François-Xavier ; Leclercq, Roland ; Less -
Description:
Shigella sonnei UCN59, isolated during an outbreak of S. sonnei in January 2007, was resistant to azithromycin (MIC 64 mg/L). The isolate contained a plasmid-borne mph(A) gene encoding a macrolide 2 -phosphotransferase that inactivates macrolides. Emergence of the mph(A) gene in S. sonnei may limit usefulness of azithromycin for treatment of shigellosis.
Subject:
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Anti-Bacterial Agents
Antibiotic Resistance
Azithromycin
Child, Preschool
Disease Outbreaks
Dispatch
Drug Resistance, Multiple, Bacterial
Dysentery, Bacillary
Electrophoresis, Gel, Pulsed-Field
Female
Humans
Macrolides
Outbreak
Phylogeny
Polymerase Chain Reaction
Shigella Sonnei
Shigellosis
Surveillance

Source:
Emerg Infect Dis. 14(8):1297-1299. ;
Document Type:
Journal Article ;
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:4324412dad021457ab9c3e4dbe34935a26e25d188b2b81f46ef442fdb248e1ab
File Type:

Supporting Files

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  	08-0147_finalD.nxml	txt
  	license.txt	txt

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