Macrolide-Resistant Shigella sonnei

Boumghar-Bourtchai, Leyla; Mariani-Kurkdjian, Patricia; Bingen, Edouard; Filliol, Ingrid; Dhalluin, Anne; Ifrane, Shadia Ait; Weill, François-Xavier; Leclercq, Roland

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Macrolide-Resistant Shigella sonnei

Supporting Files Public Domain

Aug 2008
By Boumghar-Bourtchai, Leyla ; Mariani-Kurkdjian, Patricia ; Bingen, Edouard ; ...

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Alternative Title:

Emerg Infect Dis
Personal Author:

Boumghar-Bourtchai, Leyla ; Mariani-Kurkdjian, Patricia ; Bingen, Edouard ; Filliol, Ingrid ; Dhalluin, Anne ; Ifrane, Shadia Ait ; Weill, François-Xavier ; Leclercq, Roland
Description:

Shigella sonnei UCN59, isolated during an outbreak of S. sonnei in January 2007, was resistant to azithromycin (MIC 64 mg/L). The isolate contained a plasmid-borne mph(A) gene encoding a macrolide 2 -phosphotransferase that inactivates macrolides. Emergence of the mph(A) gene in S. sonnei may limit usefulness of azithromycin for treatment of shigellosis.
Subjects:

Anti-Bacterial Agents Antibiotic Resistance Azithromycin Child, Preschool Disease Outbreaks Dispatch Drug Resistance, Multiple, Bacterial Dysentery, Bacillary Electrophoresis, Gel, Pulsed-Field Female Humans Macrolides Outbreak Phylogeny Polymerase Chain Reaction Shigella Sonnei Shigellosis Surveillance
Source:

Emerg Infect Dis. 14(8):1297-1299.
Document Type:

Journal Article
Volume:

14
Issue:

8
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:4324412dad021457ab9c3e4dbe34935a26e25d188b2b81f46ef442fdb248e1ab
Download URL:

https://stacks.cdc.gov/view/cdc/17212/cdc_17212_DS1.pdf
File Type:

[PDF - 193.20 KB ]

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