Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
van den Wijngaard, Cees ; van Asten, Liselotte ; van Pelt, Wilfrid ; Nagelkerke, Nico J.D. ; Verheij, Robert ; ... More +
van den Wijngaard, Cees ; van Asten, Liselotte ; van Pelt, Wilfrid ; Nagelkerke, Nico J.D. ; Verheij, Robert ; de Neeling, Albert J. ; Dekkers, Arnold ; van der Sande, Marianne A.B. ; van Vliet, Hans ; Koopmans, Marion P.G. Less -
Description:
Syndromic surveillance is increasingly used to signal unusual illness events. To validate data-source selection, we retrospectively investigated the extent to which 6 respiratory syndromes (based on different medical registries) reflected respiratory pathogen activity. These syndromes showed higher levels in winter, which corresponded with higher laboratory counts of Streptococcus pneumoniae, respiratory syncytial virus, and influenza virus. Multiple linear regression models indicated that most syndrome variations (up to 86%) can be explained by counts of respiratory pathogens. Absenteeism and pharmacy syndromes might reflect nonrespiratory conditions as well. We also observed systematic syndrome elevations in the fall, which were unexplained by pathogen counts but likely reflected rhinovirus activity. Earliest syndrome elevations were observed in absenteeism data, followed by hospital data (+1 week), pharmacy/general practitioner consultations (+2 weeks), and deaths/laboratory submissions (test requests) (+3 weeks). We conclude that these syndromes can be used for respiratory syndromic surveillance, since they reflect patterns in respiratory pathogen activity.
Subject:
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Absenteeism
Communicable Diseases, Emerging
Family Practice
Hospitalization
Humans
Pharmacy
Population Surveillance
Registries
Research
Respiratory Tract Infections
Syndrome
Virus Diseases
Viruses

Source:
Emerg Infect Dis. 14(6):917-925.
Document Type:
Journal Article
Place as Subject:
Netherlands
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:40d5f6caa2a45ba5af7b48ad8e6767ef05ef449dd42be883eabd69deb75bdab5
File Type:

Supporting Files

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  	07-1467-F1.jpg	jpeg
  	07-1467-F2.gif	gif
  	07-1467-F2.jpg	jpeg
  	07-1467_finalR.nxml	txt
  	07-1467_Techapp-s1.pdf	pdf

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