Integrating Host Genomics with Surveillance for Invasive Bacterial Diseases

Crawford, Dana C.; Zimmer, Shanta M.; Morin, Craig A.; Messonnier, Nancy E.; Lynfield, Ruth; Yi, Qian; Shephard, Cynthia; Wong, Michelle; Rieder, Mark J.; Livingston, Robert J.; Nickerson, Deborah A.; Whitney, Cynthia G.; Lingappa, Jairam

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CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners. As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.

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Integrating Host Genomics with Surveillance for Invasive Bacterial Diseases

Jul 2008
By Crawford, Dana C. ; Zimmer, Shanta M. ; Morin, Craig A. ; ...
Source: Emerg Infect Dis. 14(7):1138-1140.

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Crawford, Dana C. ; Zimmer, Shanta M. ; Morin, Craig A. ; Messonnier, Nancy E. ; Lynfield, Ruth ; ... More +

Crawford, Dana C. ; Zimmer, Shanta M. ; Morin, Craig A. ; Messonnier, Nancy E. ; Lynfield, Ruth ; Yi, Qian ; Shephard, Cynthia ; Wong, Michelle ; Rieder, Mark J. ; Livingston, Robert J. ; Nickerson, Deborah A. ; Whitney, Cynthia G. ; Lingappa, Jairam Less -
Description:

We tested the feasibility of linking Active Bacterial Core surveillance, a prospective, population-based surveillance system for invasive bacterial disease, to a newborn dried blood spot (nDBS) repository. Using nDBS specimens, we resequenced CD46, putative host gene receptor for Neisseria meningitidis, and identified variants associated with susceptibility to this disease.
Subjects:

[+]

Active Bacterial Core Surveillance Antigens, CD46 Blood Spots Case-Control Studies CD46 Child, Preschool Dispatch Feasibility Studies Genetic Predisposition To Disease Host Gene Humans Infant Infant, Newborn Meningitis, Bacterial Neisseria Meningitidis Neonatal Screening Polymorphism, Single Nucleotide Population Surveillance Retrospective Studies
Source:

Emerg Infect Dis. 14(7):1138-1140.
Document Type:

Journal Article
Volume:

14
Issue:

7
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:48685d8f3afc2e47b9006efa71cc132202583fb3490335afd6902819e35c8235
Download URL:

https://stacks.cdc.gov/view/cdc/17062/cdc_17062_DS1.pdf
File Type:

[PDF-139.82 KB]

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