Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Wölfel, Roman; Paweska, Janusz T.; Petersen, Nadine; Grobbelaar, Antoinette A.; Leman, Patricia A.; ... More +
Wölfel, Roman; Paweska, Janusz T.; Petersen, Nadine; Grobbelaar, Antoinette A.; Leman, Patricia A.; Hewson, Roger; Georges-Courbot, Marie-Claude; Papa, Anna; Günther, Stephan; Drosten, Christian; Less -
Description:
We developed a real-time reverse transcription--PCR that detected 1,164 copies/mL of Crimean-Congo hemorrhagic fever virus per milliliter of serum at 95% probability (probit analysis) and was 100% concordant with nested PCR on 63 samples from 31 patients with confirmed infection. Infected patients who died appeared to have higher viral loads; low viral loads correlated with IgG detection.
Subject:
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5′-nuclease Assay
Crimean-Congo Hemorrhagic Fever Virus
Dispatch
Genetic Variation
Hemorrhagic Fever, Crimean
Hemorrhagic Fever Virus, Crimean-Congo
Humans
Phylogeny
Reproducibility Of Results
Reverse Transcriptase Polymerase Chain Reaction
RT-PCR
Sensitivity And Specificity
Species Specificity
Viral Load

Source:
Emerg Infect Dis. 13(7):1097-1100.;
Document Type:
Journal Article;
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:e8eaaec53195f66e7abb8323ac1dc4e07ae63019e586223379e378b040a282ac
File Type:

Supporting Files

• 	license.txt	txt
  	07-0068-F1.gif	gif
  	07-0068-F1.jpg	jpeg
  	07-0068-F2.gif	gif
  	07-0068-F2.jpg	jpeg
  	07-0068_appT-s1.pdf	pdf
  	07-0068_finalD.nxml	txt

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