Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Brown, Justin D. ; Stallknecht, David E. ; Beck, Joan R. ; Suarez, David L. ; Swayne, David E.
Brown, Justin D. ; Stallknecht, David E. ; Beck, Joan R. ; Suarez, David L. ; Swayne, David E. Less -
Description:
Since 2002, H5N1 highly pathogenic avian influenza (HPA1) viruses have been associated with deaths in numerous wild avian species throughout Eurasia. We assessed the clinical response and extent and duration of viral shedding in 5 species of North American ducks and laughing gulls (Larus atricilla) after intranasal challenge with 2 Asian H5N1 HPAI viruses. Birds were challenged at approximately equal to 10 to 16 weeks of age, consistent with temporal peaks in virus prevalence and fall migration. All species were infected, but only wood ducks (Aix sponsa) and laughing gulls exhibited illness or died. Viral titers were higher in oropharyngeal swabs than in cloacal swabs. Duration of viral shedding (1-10 days) increased with severity of clinical disease. Both the hemagglutination-inhibition (HI) and agar gel precipitin (AGP) tests were able to detect postinoculation antibodies in surviving wood ducks and laughing gulls; the HI test was more sensitive than the AGP in the remaining 4 species.
Subject:
[+]
Animals
Antibodies, Viral
Avian Influenza Virus
Charadriiformes
Ducks
Gulls
H5N1
Hemagglutination Inhibition Tests
Highly Pathogenic Avian Influenza
Influenza A Virus, H5N1 Subtype
Influenza In Birds
Research
Wild Birds
Ducks

Source:
Emerg Infect Dis. 12(11):1663-1670.
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:0906e6c472c5ab59ab50c0373fb9c69f551c4911ccd41d0135c765d88dcce382
File Type:

Supporting Files

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