Multidrug-resistant Mycobacterium tuberculosis, Bangui, Central African Republic

Nouvel, Laurent X.; Kassa-Kelembho, Eric; Dos Vultos, Tiago; Zandanga, Germain; Rauzier, Jean; Lafoz, Carmen; Martin, Carlos; Blazquez, Jesus; Talarmin, Antoine; Gicquel, Brigitte

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Multidrug-resistant Mycobacterium tuberculosis, Bangui, Central African Republic

Published Date:

Sep 2006

Source:

Emerg Infect Dis. 12(9):1454-1456.

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Emerg Infect Dis

Personal Author:

Nouvel, Laurent X. ; Kassa-Kelembho, Eric ; Dos Vultos, Tiago ; Zandanga, Germain ; Rauzier, Jean ; ... More ▼

Description:

We investigated multidrug-resistant (MDR) Mycobacterium tuberculosis strains in Bangui, Central African Republic. We found 39.6% with the same spoligotype and synonymous single nucleotide polymorphism in the mutT1 gene. However, strains had different rpoB mutations responsible for rifampin resistance. MDR strains in Bangui may emerge preferentially from a single, MDR-prone family.

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Journal Article

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Emerging Infectious Diseases

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Multidrug-resistant Mycobacterium tuberculosis, Bangui, Central African Republic

Multidrug-resistant Mycobacterium tuberculosis, Bangui, Central African Republic

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