Multidrug-resistant Mycobacterium tuberculosis, Bangui, Central African Republic

Nouvel, Laurent X.; Kassa-Kelembho, Eric; Dos Vultos, Tiago; Zandanga, Germain; Rauzier, Jean; Lafoz, Carmen; Martin, Carlos; Blazquez, Jesus; Talarmin, Antoine; Gicquel, Brigitte

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Multidrug-resistant Mycobacterium tuberculosis, Bangui, Central African Republic

Sep 2006
By Nouvel, Laurent X. ; Kassa-Kelembho, Eric ; Dos Vultos, Tiago ; ...
Source: Emerg Infect Dis. 12(9):1454-1456.

[PDF-79.94 KB]

English

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Nouvel, Laurent X. ; Kassa-Kelembho, Eric ; Dos Vultos, Tiago ; Zandanga, Germain ; Rauzier, Jean ; ... More +

Nouvel, Laurent X. ; Kassa-Kelembho, Eric ; Dos Vultos, Tiago ; Zandanga, Germain ; Rauzier, Jean ; Lafoz, Carmen ; Martin, Carlos ; Blazquez, Jesus ; Talarmin, Antoine ; Gicquel, Brigitte Less -
Description:

We investigated multidrug-resistant (MDR) Mycobacterium tuberculosis strains in Bangui, Central African Republic. We found 39.6% with the same spoligotype and synonymous single nucleotide polymorphism in the mutT1 gene. However, strains had different rpoB mutations responsible for rifampin resistance. MDR strains in Bangui may emerge preferentially from a single, MDR-prone family.
Subjects:

[+]

Antitubercular Agents Bacterial Proteins DNA Repair Humans Mutation Mycobacterium Tuberculosis Oligonucleotides Polymorphism, Single Nucleotide Tuberculosis, Multidrug-Resistant
Source:

Emerg Infect Dis. 12(9):1454-1456.
Document Type:

Journal Article
Genre:

Dispatch
Place as Subject:

Central African Republic
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:d4222204586b2d64a281b9b762eccb3ca9f1be6e1b5f01aa40cffbf83ef7b976
Download URL:

https://stacks.cdc.gov/view/cdc/16291/cdc_16291_DS1.pdf
File Type:

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