Multidrug-resistant Mycobacterium tuberculosis, Bangui, Central African Republic

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Nouvel, Laurent X. ; Kassa-Kelembho, Eric ; Dos Vultos, Tiago ; Zandanga, Germain ; Rauzier, Jean ; Lafoz, Carmen ; Martin, Carlos ; Blazquez, Jesus ; Talarmin, Antoine ; Gicquel, Brigitte
• Description:
  We investigated multidrug-resistant (MDR) Mycobacterium tuberculosis strains in Bangui, Central African Republic. We found 39.6% with the same spoligotype and synonymous single nucleotide polymorphism in the mutT1 gene. However, strains had different rpoB mutations responsible for rifampin resistance. MDR strains in Bangui may emerge preferentially from a single, MDR-prone family.
• Subjects:
  Antitubercular Agents Bacterial Proteins DNA Repair Humans Mutation Mycobacterium Tuberculosis Oligonucleotides Polymorphism, Single Nucleotide Tuberculosis, Multidrug-Resistant
• Source:
  Emerg Infect Dis. 12(9):1454-1456.
• Document Type:
  Journal Article
• Genre:
  Dispatch
• Place as Subject:
  Central African Republic
• Volume:
  12
• Issue:
  9
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:d4222204586b2d64a281b9b762eccb3ca9f1be6e1b5f01aa40cffbf83ef7b976
• Download URL:
  https://stacks.cdc.gov/view/cdc/16291/cdc_16291_DS1.pdf
• File Type:
  [PDF - 79.94 KB ]