Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Nouvel, Laurent X. ; Kassa-Kelembho, Eric ; Dos Vultos, Tiago ; Zandanga, Germain ; Rauzier, Jean ; ... More +
Nouvel, Laurent X. ; Kassa-Kelembho, Eric ; Dos Vultos, Tiago ; Zandanga, Germain ; Rauzier, Jean ; Lafoz, Carmen ; Martin, Carlos ; Blazquez, Jesus ; Talarmin, Antoine ; Gicquel, Brigitte Less -
Description:
We investigated multidrug-resistant (MDR) Mycobacterium tuberculosis strains in Bangui, Central African Republic. We found 39.6% with the same spoligotype and synonymous single nucleotide polymorphism in the mutT1 gene. However, strains had different rpoB mutations responsible for rifampin resistance. MDR strains in Bangui may emerge preferentially from a single, MDR-prone family.
Subject:
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Antibiotic Resistance
Antitubercular Agents
Bacterial Proteins
Central African Republic
Dispatch
DNA Repair
Humans
Molecular Epidemiology
Mutation
Mycobacterium Tuberculosis
Oligonucleotides
Polymorphism, Single Nucleotide
Tuberculosis
Tuberculosis, Multidrug-Resistant

Source:
Emerg Infect Dis. 12(9):1454-1456.
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:d4222204586b2d64a281b9b762eccb3ca9f1be6e1b5f01aa40cffbf83ef7b976
File Type:

Supporting Files

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  	license.txt	txt

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