Human Rotavirus Serotype G9, São Paulo, Brazil, 1996–2003

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Carmona, Rita Cássia Compagnoli ; Timenetsky, Maria do Carmo Sampaio Tavares ; Morillo, Simone Guadagnucci ; Richtzenhain, Leonardo José
• Description:
  A total of 3,101 fecal specimens were collected during an 8-year survey for rotavirus infection in São Paulo, Brazil. Group A rotavirus was detected in 774 (25.0%) specimens. Of these, 431 strains (55.7%) were analyzed for G and P types by reverse transcription-polymerase chain reaction; G1 was the predominant serotype (68.2%), followed by G9 (17.2%), G4 (6.3%), G2 (1.2%), G3 (0.7%), mixed infection (1.8%), and untypeable (4.6%). Both rotavirus G and P types could be established in 332 strains (77.0%). We identified the 4 most common strains worldwide: P8G1 (66.6%), P4G2 (1.0%), P8G3 (0.6%), and P8G4 (7.2%). Among the single G9 strains detected, VP4 genotyping showed that P8G9 was the most prevalent, followed by P4G9 and P6G9. The emergence and high frequency of rotavirus G9 in São Paulo, Brazil, and other parts of the world will affect the development and evaluation of future vaccines.
• Subjects:
  • Adolescent
  • Adult
  • Capsid Proteins
  • Child
  • Child, Preschool
  • Diarrhea
  • Enzyme-Linked Immunosorbent Assay
  • Feces
  • Humans
  • Middle Aged
  More +
• Source:
  Emerg Infect Dis. 12(6):963-968.
• Document Type:
  Journal Article
• Place as Subject:
  Brazil
• Volume:
  12
• Issue:
  6
• Download URL:
  https://stacks.cdc.gov/view/cdc/16273/cdc_16273_DS1.pdf
• File Type:
  [PDF - 215.72 KB]
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:fc801dc46f07f8f8377c2f7f1c2384f3d0ad726ca3f59381e3e0ac4af792a126