Transmission of New Bovine Prion to Mice

Baron, Thierry G.M.; Biacabe, Anne-Gaëlle; Bencsik, Anna; Langeveld, Jan P.M.

i

Transmission of New Bovine Prion to Mice

Supporting Files Public Domain

Jul 2006
By Baron, Thierry G.M. ; Biacabe, Anne-Gaëlle ; Bencsik, Anna ; ...

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Baron, Thierry G.M. ; Biacabe, Anne-Gaëlle ; Bencsik, Anna ; Langeveld, Jan P.M.
Description:

We previously reported that cattle were affected by a prion disorder that differed from bovine spongiform encephalopathy (BSE) by showing distinct molecular features of disease-associated protease-resistant prion protein (PrP(res). We show that intracerebral injection of such isolates into C57BL/6 mice produces a disease with preservation of PrP(res) molecular features distinct from BSE.
Subjects:

Animals Bovine Spongiform Encephalopathy Brain Cattle Dispatch Female Mice Mice, Inbred C57BL Prion Prion Diseases Prions
Source:

Emerg Infect Dis. 12(7):1125-1128.
Document Type:

Journal Article
Volume:

12
Issue:

7
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:c10159024f7f22e4d6136467d34b047d42a9fed19f45437dcd1286d719a0df2e
Download URL:

https://stacks.cdc.gov/view/cdc/16223/cdc_16223_DS1.pdf
File Type:

[PDF - 302.92 KB ]

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