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Transmission of New Bovine Prion to Mice
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Jul 2006
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Source: Emerg Infect Dis. 12(7):1125-1128.
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Alternative Title:Emerg Infect Dis
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Description:We previously reported that cattle were affected by a prion disorder that differed from bovine spongiform encephalopathy (BSE) by showing distinct molecular features of disease-associated protease-resistant prion protein (PrP(res). We show that intracerebral injection of such isolates into C57BL/6 mice produces a disease with preservation of PrP(res) molecular features distinct from BSE.
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