VEB-1 Extended-Spectrum β-lactamase–producing Acinetobacter baumannii, France

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Naas, Thierry ; Coignard, Bruno ; Carbonne, Anne ; Blanckaert, Karine ; Bajolet, Odile ; Bernet, Claude ; Verdeil, Xavier ; Astagneau, Pascal ; Desenclos, Jean-Claude ; Nordmann, Patrice
• Corporate Authors:
  on behalf of ; French Nosocomial Infection Early Warning, Investigation and Surveillance Network
• Description:
  VEB-1 extended-spectrum beta-lactamase-producing Acinetobacter baumannii was responsible for an outbreak in hospitals in France. A national alert was triggered in September 2003 when 4 hospitals reported clusters of A. baumannii infection with similar susceptibility profiles. Case definitions and laboratory guidelines were disseminated, and prospective surveillance was implemented; strains were sent to a single laboratory for characterization and typing. From April 2003 through June 2004, 53 hospitals reported 290 cases of A. baumannii infection or colonization; 275 isolates were bla(VEB-1)-positive and clonally related. Cases were first reported in 5 districts of northern France, then in 10 other districts in 4 regions. Within a region, interhospital spread was associated with patient transfer. In northern France, investigation and control measures led to a reduction of reported cases after January 2004. The national alert enabled early control of new clusters, demonstrating the usefulness of early warning about antimicrobial drug resist.
• Subjects:
  Acinetobacter Baumannii Acinetobacter Infections Beta-Lactamases Beta-Lactam Resistance Cross Infection Disease Outbreaks Hospitals Humans Infection Control Microbial Sensitivity Tests Population Surveillance

  More +
• Source:
  Emerg Infect Dis. 12(8):1214-1222.
• Document Type:
  Journal Article
• Place as Subject:
  France
• Volume:
  12
• Issue:
  8
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:39db3ea04b47aa72b09cb50e00e2358b11b985236564450d5d4a50113ad149af
• Download URL:
  https://stacks.cdc.gov/view/cdc/16167/cdc_16167_DS1.pdf
• File Type:
  [PDF - 394.37 KB ]