Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Naas, Thierry ; Coignard, Bruno ; Carbonne, Anne ; Blanckaert, Karine ; Bajolet, Odile ; ... More +
Naas, Thierry ; Coignard, Bruno ; Carbonne, Anne ; Blanckaert, Karine ; Bajolet, Odile ; Bernet, Claude ; Verdeil, Xavier ; Astagneau, Pascal ; Desenclos, Jean-Claude ; Nordmann, Patrice Less -
Corporate Authors:
on behalf of ; French Nosocomial Infection Early Warning, Investigation and Surveillance Network
on behalf of ; French Nosocomial Infection Early Warning, Investigation and Surveillance Network Less -
Description:
VEB-1 extended-spectrum beta-lactamase-producing Acinetobacter baumannii was responsible for an outbreak in hospitals in France. A national alert was triggered in September 2003 when 4 hospitals reported clusters of A. baumannii infection with similar susceptibility profiles. Case definitions and laboratory guidelines were disseminated, and prospective surveillance was implemented; strains were sent to a single laboratory for characterization and typing. From April 2003 through June 2004, 53 hospitals reported 290 cases of A. baumannii infection or colonization; 275 isolates were bla(VEB-1)-positive and clonally related. Cases were first reported in 5 districts of northern France, then in 10 other districts in 4 regions. Within a region, interhospital spread was associated with patient transfer. In northern France, investigation and control measures led to a reduction of reported cases after January 2004. The national alert enabled early control of new clusters, demonstrating the usefulness of early warning about antimicrobial drug resist.
Subject:
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Acinetobacter Baumannii
Acinetobacter Infections
Beta-Lactamases
Beta-Lactam Resistance
Cross Infection
Disease Outbreaks
Hospitals
Humans
Infection Control
Microbial Sensitivity Tests
Population Surveillance

Source:
Emerg Infect Dis. 12(8):1214-1222.
Document Type:
Journal Article
Place as Subject:
France
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:39db3ea04b47aa72b09cb50e00e2358b11b985236564450d5d4a50113ad149af
File Type:

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