Donor-derived transmission through lung transplantation of carbapenem-resistant Acinetobacter baumannii producing the OXA-23 carbapenemase during an ongoing healthcare facility outbreak

Details

• Alternative Title:
  Transpl Infect Dis
• Personal Author:
  Bardossy, Ana C. ; Snavely, Emily A. ; Nazarian, Elizabeth ; Annambhotla, Pallavi ; Basavaraju, Sridhar V. ; Pepe, Dana ; Maloney, Meghan ; Musser, Kimberlee A. ; Haas, Wolfgang ; Barros, Nicolas ; Pierce, Virginia M. ; Walters, Maroya ; Epstein, Lauren
• Description:
  We describe a rare instance of donor-derived OXA-23-producing carbapenem-resistant Acinetobacter baumannii transmission during lung transplantation and the subsequent public health response. This investigation highlights how transplantation can introduce rare multidrug-resistant organisms into different healthcare facilities and regions.
• Subjects:
  Acinetobacter Baumannii Acinetobacter Infections Beta-Lactamases Beta-Lactam Resistance Carbapenems Disease Outbreaks Drug Resistance, Multiple, Bacterial Genotype Health Facilities Humans Lung Transplantation Male Microbial Sensitivity Tests Middle Aged Phenotype Sputum Tissue Donors

  More +
• Keywords:
  Carbapenem-resistant Acinetobacter Baumannii Donor-derived Transmission Lung Transplantation
• Source:
  Transpl Infect Dis. 22(2):e13256
• Pubmed ID:
  32034865
• Pubmed Central ID:
  PMC10833477
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Volume:
  22
• Issue:
  2
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:625b8136bc3ec934a20494ef455596b2ea8b9a0b1c1ac46aced71831716b4d8da7e23a68850d41a147c2b4fa381a2309b858ac73bf31d6e4c48a818060ecf8cc
• Download URL:
  https://stacks.cdc.gov/view/cdc/147672/cdc_147672_DS1.pdf
• File Type:
  [PDF - 145.11 KB ]