Molecular Analysis of Fluoroquinolone-resistant Salmonella Paratyphi A Isolate, India

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Nair, Satheesh ; Unnikrishnan, Madhulika ; Turner, Keith ; Parija, Subash Chandra ; Churcher, Carol ; Wain, John ; Harish, Belgode Narasimha
• Description:
  Salmonella enterica serovar Paratyphi A is increasingly a cause of enteric fever. Sequence analysis of an Indian isolate showed a unique strain with high-level resistance to ciprofloxacin associated with double mutations in the DNA gyrase subunit gyrA (Ser83-->Phe and Asp87-->Gly) and a mutation in topoisomerase IV subunit parC (Ser80-->Arg).
• Subjects:
  Anti-Bacterial Agents Dispatch DNA, Bacterial DNA Gyrase DNA Topoisomerase IV Drug Resistance, Multiple, Bacterial Mutation Salmonella Paratyphi A
• Source:
  Emerg Infect Dis. 12(3):489-491.
• Document Type:
  Journal Article
• Place as Subject:
  India
• Location:
  Asia
• Volume:
  12
• Issue:
  3
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:3174b8e22e6a5d500b75da23cd5a3e371efdcdd33d78ae8483c6691feefeefcd
• Download URL:
  https://stacks.cdc.gov/view/cdc/15929/cdc_15929_DS1.pdf
• File Type:
  [PDF - 82.39 KB ]