Hidden Epidemic of Macrolide-resistant Pneumococci

Klugman, Keith P.; Lonks, John R.

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Hidden Epidemic of Macrolide-resistant Pneumococci

Jun 2005
By Klugman, Keith P. ; Lonks, John R.
Source: Emerg Infect Dis. 11(6):802-807.

[PDF-208.63 KB]

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Klugman, Keith P. ; Lonks, John R.

Klugman, Keith P. ; Lonks, John R. Less -
Description:

Community-acquired respiratory tract infections (RTIs) account for a substantial proportion of outpatient antimicrobial drug prescriptions worldwide. Concern over the emergence of multidrug resistance in pneumococci has largely been focused on penicillin-resistant Streptococcus pneumoniae. Macrolide antimicrobial drugs have been widely used to empirically treat community-acquired RTIs because of their efficacy in treating both common and atypical respiratory pathogens, including S. pneumoniae. However, increased macrolide use has been associated with a global increase in pneumococcal resistance, which is leading to concern over the continued clinical efficacy of the macrolides to treat community-acquired RTIs. We provide an overview of macrolide-resistant S. pneumoniae and assess the impact of this resistance on the empiric treatment of community-acquired RTIs.
Subjects:

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Anti-Bacterial Agents Community-acquired Infections Disease Outbreaks Drug Resistance, Bacterial Humans Keywords: Antibiotic Resistance Macrolides Perspective Pneumonia, Pneumococcal Respiratory Tract Infections Streptococcus Pneumoniae Treatment Failure
Source:

Emerg Infect Dis. 11(6):802-807.
Document Type:

Journal Article
Volume:

11
Issue:

6
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:1ce8ce41a083f1766ae47191d74f410f4277599d87a6d0653b34f7eee21df99d
Download URL:

https://stacks.cdc.gov/view/cdc/15842/cdc_15842_DS1.pdf
File Type:

	05-0147.nxml	txt
	license.txt	txt

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