Antimicrobial Resistance as Risk Factor for Recurrent Bacteremia after Staphylococcusaureus, Escherichia coli, or Klebsiella spp. Community-Onset Bacteremia

Abbara, Salam; Guillemot, Didier; Smith, David R.M.; El Oualydy, Salma; Kos, Maeva; Poret, Cécile; Breant, Stéphane; Brun-Buisson, Christian; Watier, Laurence

doi:10.3201/eid3005.231555

Advanced Search

Select up to three search categories and corresponding keywords using the fields to the right. Refer to the Help section for more detailed instructions.

Search our Collections & Repository

Advanced Search
Custom Query

All these words:

For very narrow results

This exact word or phrase:

When looking for a specific result

Any of these words:

Best used for discovery & interchangable words

None of these words:

Recommended to be used in conjunction with other fields

Language:

Dates

Publication Date Range:

to

Document Data

Title:

Document Type:

Library

Collection:

Series:

People

Author:

Clear All

Query Builder

Query box

Clear All

For additional assistance using the Custom Query please check out our Help Page

i

Antimicrobial Resistance as Risk Factor for Recurrent Bacteremia after Staphylococcusaureus, Escherichia coli, or Klebsiella spp. Community-Onset Bacteremia

5 2024
By Abbara, Salam ; Guillemot, Didier ; Smith, David R.M. ; ...
http://dx.doi.org/10.3201/eid3005.231555
Source: Emerg Infect Dis. 2024; 30(5):974-983

[PDF-756.04 KB]

English

Details Supporting Files You May Also Like

Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Abbara, Salam ; Guillemot, Didier ; Smith, David R.M. ; El Oualydy, Salma ; Kos, Maeva ; ... More +

Abbara, Salam ; Guillemot, Didier ; Smith, David R.M. ; El Oualydy, Salma ; Kos, Maeva ; Poret, Cécile ; Breant, Stéphane ; Brun-Buisson, Christian ; Watier, Laurence Less -
Description:

We investigated links between antimicrobial resistance in community-onset bacteremia and 1-year bacteremia recurrence by using the clinical data warehouse of Europe's largest university hospital group in France. We included adult patients hospitalized with an incident community-onset Staphylococcus aureus, Escherichia coli, or Klebsiella spp. bacteremia during 2017-2019. We assessed risk factors of 1-year recurrence using Fine-Gray regression models. Of the 3,617 patients included, 291 (8.0%) had >1 recurrence episode. Third-generation cephalosporin (3GC)-resistance was significantly associated with increased recurrence risk after incident Klebsiella spp. (hazard ratio 3.91 [95% CI 2.32-6.59]) or E. coli (hazard ratio 2.35 [95% CI 1.50-3.68]) bacteremia. Methicillin resistance in S. aureus bacteremia had no effect on recurrence risk. Although several underlying conditions and infection sources increased recurrence risk, 3GC-resistant Klebsiella spp. was associated with the greatest increase. These results demonstrate a new facet to illness induced by 3GC-resistant Klebsiella spp. and E. coli in the community setting.
Subjects:

[+]

Adult Aged Anti-Bacterial Agents Bacteremia Community-Acquired Infections Drug Resistance, Bacterial Escherichia Coli Escherichia Coli Infections Female Humans Klebsiella Klebsiella Infections Male Middle Aged Recurrence Risk Factors Staphylococcal Infections Staphylococcus Aureus
Keywords:

[+]

Antimicrobial Resistance Bacteremia Bacteria Community-acquired Infections Drug Resistance France Recurrence
Source:

Emerg Infect Dis. 2024; 30(5):974-983
Pubmed ID:

38666612
Pubmed Central ID:

PMC11060452
Document Type:

Journal Article
Place as Subject:

France
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:f98a5585f0aae9110fec30478aeedb7a850ef6575811764b1c649a35186e8fe0
Download URL:

https://stacks.cdc.gov/view/cdc/154870/cdc_154870_DS1.pdf
File Type:

	23-1555-F1.gif	gif
	23-1555-F1.jpg	jpeg
	23-1555-F2.gif	gif
	23-1555-F2.jpg	jpeg
	23-1555-Techapp-s1.pdf	pdf
	23-1555.nxml	xml

More +