Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Jenkins, Claire ; Claxton, Alleyna P. ; Shorten, Robert J. ; McHugh, Timothy D. ; Gillespie, Stephen H.
Jenkins, Claire ; Claxton, Alleyna P. ; Shorten, Robert J. ; McHugh, Timothy D. ; Gillespie, Stephen H. Less -
Description:
Mycobacterium tuberculosis isolates cultured from 6 patients associated with an isoniazid-resistant M. tuberculosis outbreak acquired rifampicin resistance. The rpoB gene sequence showed that resistance was associated with rare mutations in each isolate. Three isolates had a mutation outside the rifampicin resistance-determining region.
Subject:
[+]
Antitubercular Agents
Base Sequence
Disease Outbreaks
Dispatch
DNA-Directed RNA Polymerases
Drug Resistance, Bacterial
Humans
Isoniazid
Keywords: Multi-drug Resistant Mycobacterium Tuberculosis
London
Molecular Sequence Data
Mutation
Mycobacterium Tuberculosis
Rare Mutations
Rifampin
Sequencing
Tuberculosis, Multidrug-Resistant
Tuberculosis, Pulmonary

Source:
Emerg Infect Dis. 11(6):931-934.
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:de3e16a58eb789c670ed8a14042b23141dcab76425b550a6679649cfbeea7091
File Type:

Supporting Files

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  	04-1262.nxml	txt
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