CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners.
As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.
i
Molecular identification of streptomycin monoresistant Mycobacterium tuberculosis related to multidrug-resistant W strain.
-
2001 Sep-Oct
-
-
Source: Emerg Infect Dis. 7(5):842-848.
Details:
-
Alternative Title:Emerg Infect Dis
-
Personal Author:
-
Description:A distinct branch of the Mycobacterium tuberculosis W phylogenetic lineage (W14 group) has been identified and characterized by various genotyping techniques. The W14 group comprises three strain variants: W14, W23, and W26, which accounted for 26 clinical isolates from the New York City metropolitan area. The W14 group shares a unique IS6110 hybridizing banding motif as well as distinct polymorphic GC-rich repetitive sequence and variable number tandem repeat patterns. All W14 group members have high levels of streptomycin resistance. When the streptomycin resistance rpsL target gene was sequenced, all members of this strain family had an identical mutation in codon 43. Patients infected with the W14 group were primarily of non- Hispanic black origin (77%); all were US-born. Including HIV positivity, 84% of the patients had at least one known risk factor for tuberculosis.
-
Subjects:
-
Source:
-
Document Type:
-
Place as Subject:
-
Volume:7
-
Issue:5
-
Collection(s):
-
Main Document Checksum:
-
Download URL:
-
File Type: