Cognitive Complaint Types Can Correlate with Cognitive Testing, Perceived Stress, and Symptom Distress in Older Adults with Normal Cognition and Dementia

Details

• Alternative Title:
  Alzheimer Dis Assoc Disord
• Personal Author:
  Stites, Shana D. ; Lee, Brian N. ; Rubright, Jonathan D. ; Harkins, Kristin ; Mechanic-Hamilton, Dawn
• Description:
  Objective.
  
  We examined how cognitive complaint types (CCTs) correlate with cognitive testing, perceived stress, and symptom distress in older adults with normal cognition and dementia.
  
  Method.
  
  Older adults (n=259) with normal cognition, Mild Cognitive Impairment (MCI), or mild stage Alzheimer’s disease completed cognitive testing and self-report measures (Cognitive Difficulties Scale [CDS], Global Distress Index [GDI], Perceived Stress Scale [PSS]). Cross-sectional analyses examined: 1) CCTs composition by classification method, 2) CCTs by diagnostic group, 3) correlations of CCTs with cognitive testing scores, and 4) correlations of CCTs with perceived stress and symptom distress.
  
  Results.
  
  CCTs derived from 2 classification approaches loaded onto four factors: Memory, Attention-Concentration, Temporal Orientation, and Praxis. Memory contained complaints about both memory and executive functioning. Attention-Concentration contained both classifications of attention-concentration (AC) complaints. Complaints about Attention-Concentration (AC1, AC2) differed by diagnostic group (all p<0.05). One of 2 classifications of Attention-Concentration (AC1) complaints discerned between impaired and unimpaired long-delay memory scores (both p<0.05). In multivariable analyses, that same classification of Attention-Concentration (AC1) complaints correlated with higher perceived stress (both p<0.001) but not symptom distress (both p>0.05).
  
  Conclusion:
  
  CCTs showed a factor structure that was mostly robust between classification methods; however, some content-divergent CCTs shared factors, suggesting construct overlap. Relatively slight variations in content altered how CCTs correlated with diagnostic groups, perceived stress, and symptom distress. Most CCTs did not discern between impaired and unimpaired cognitive test scores. Research is needed to better understand CCTs as clinical markers and targets of clinical interventions.
  
  
• Subjects:
  Aged Alzheimer Disease Cognition Cognitive Dysfunction Cross-Sectional Studies Humans Neuropsychological Tests Psychological Tests Self Report Stress, Psychological
• Keywords:
  Alzheimer’s Disease Cognitive Testing Mild Cognitive Impairment Self-reported Cognitive Complaints Subjective Cognitive Complaints
• Source:
  Alzheimer Dis Assoc Disord. 38(1):34-41
• Pubmed ID:
  38133963
• Pubmed Central ID:
  PMC10922433
• Document Type:
  Journal Article
• Funding:
  U48DP005053/ACL/ACL HHSUnited States/ ; P30 AG010124/AG/NIA NIH HHSUnited States/ ; K23 AG065499/AG/NIA NIH HHSUnited States/ ; U48 DP005053/DP/NCCDPHP CDC HHSUnited States/ ; K23 AG065442/AG/NIA NIH HHSUnited States/ ; P30 AG072979/AG/NIA NIH HHSUnited States/
• Volume:
  38
• Issue:
  1
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:4afcd4ea95c8459984af86c8b416379a0ba5075b44f3167a64e502405d5b88803454d18d4ac3f72942ea4c2f304d4d45c05bf8e41e36f5080c8eee37ea44611e
• Download URL:
  https://stacks.cdc.gov/view/cdc/151625/cdc_151625_DS1.pdf
• File Type:
  [PDF - 384.05 KB ]