Molecular Mechanisms of West Nile Virus Pathogenesis in Brain Cells

Koh, Wee-Lee; Ng, Mah-Lee

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Molecular Mechanisms of West Nile Virus Pathogenesis in Brain Cells

Supporting Files Public Domain

Apr 2005
By Koh, Wee-Lee ; Ng, Mah-Lee

File Language:

English

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Alternative Title:

Emerg Infect Dis
Personal Author:

Koh, Wee-Lee ; Ng, Mah-Lee
Description:

We analyzed the response of human glioma cells to West Nile virus infection by investigating host transcriptional changes. Changes in expression of 23 genes showed similarities to those in other neurodegenerative diseases. These changes may be useful as potential biomarkers and elucidate novel mechanisms behind the neuropathology of infection with this virus.
Subjects:

Biological Markers Brain Cell Line, Tumor Cytopathogenic Effect, Viral Gene Expression Glioblastoma Humans Microarray Analysis Reproducibility Of Results Reverse Transcriptase Polymerase Chain Reaction West Nile Fever West Nile Virus
Source:

Emerg Infect Dis. 11(4):629-632.
Document Type:

Journal Article
Volume:

11
Issue:

4
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:ac68f91dd32208f50cad6c6dd76fcc0e7b1f772b8036143fc4866b32b1d55ae8
Download URL:

https://stacks.cdc.gov/view/cdc/14736/cdc_14736_DS1.pdf
File Type:

[PDF - 97.87 KB ]

04-1076.nxml

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File Language:

English

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