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Genome Sequence and Attenuating Mutations in West Nile Virus Isolate from Mexico
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Dec 2004
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Source: Emerg Infect Dis. 10(12):2221-2224.
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Alternative Title:Emerg Infect Dis
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Description:The complete genome sequence of a Mexican West Nile virus isolate, TM171-03, included 46 nucleotide (0.42%) and 4 amino acid (0.11%) differences from the NY99 prototype. Mouse virulence differences between plaque-purified variants of TM171-03 with mutations at the E protein glycosylation motif suggest the emergence of an attenuating mutation.
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Volume:10
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Issue:12
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