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Balamuthia Amebic Encephalitis
  • Published Date:
    Aug 2004
  • Source:
    Emerg Infect Dis. 10(8):1510-1512.
Filetype[PDF-49.86 KB]


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  1. Assessment of blood-brain barrier penetration of miltefosine used to treat a fatal case of granulomatous amebic encephalitis possibly caused by an unusual Balamuthia mandrillaris strain
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    Roy, Sharon L.; Atkins, Jane T.; Gennuso, Rosemaria; Kofos, Danny; Sriram, Rama R.; Dorlo, Thomas P.C.; Hayes, Teresa; Qvarnstrom, Yvonne; Kucerova, Zuzana; Guglielmo, B. Joseph; Visvesvara, Govinda S.;
    Published:
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    Parasitol Res. 114(12):4431-4439.
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    Balamuthia mandrillaris, a free-living ameba, causes rare but frequently fatal granulomatous amebic encephalitis (GAE). Few patients have survived after receiving experimental drug combinations, with or without brain lesion excisions. Some GAE surviv...
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  2. Centrofacial Balamuthiasis: Case Report of a Rare Cutaneous Amebic Infection
    Personal Author:
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    Published:
    Jul 12 2016
    Source:
    J Cutan Pathol. 43(10):892-897.
    Description:
    Free-living amebae are ubiquitous in our environment, but rarely cause cutaneous infection. Balamuthia mandrillaris has a predilection for infecting skin of the central face. Infection may be restricted to the skin or associated with life-threatening...
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  3. Acanthamoeba Encephalitis in Patient with Systemic Lupus, India
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    Shirwadkar, Charudatt G.; Samant, Rohini; Sankhe, Milind; Deshpande, Ramesh; Yagi, Shigeo; Schuster, Frederick L.; Sriram, Rama; Visvesvara, Govinda S.;
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    Emerg Infect Dis. 12(6):984-986.
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    We report a fatal case of encephalitis caused by Acanthamoeba in a 24-year-old woman from India with systemic lupus erythematosus. Diagnosis was made by identification of amebas in brain sections by immunofluorescence analysis and confirmed by demons...
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  4. Transmission of Balamuthia mandrillaris through Solid Organ Transplantation: Utility of Organ Recipient Serology to Guide Clinical Management
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    Gupte, Asmita A.; Hocevar, Susan N.; Lea, Alfred S.; Kulkarni, Rupak D.; Schain, Denise C.; Casey, Michael J.; Zendejas-Ruiz, Ivan R.; Chung, Won K.; Mbaeyi, Chukwuma; Roy, Sharon L.; Visvesvara, Govinda S.; da Silva, Alexandre J.; Tallaj, Jose; Eckhoff, Devin; Baddley, John W.;
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    Am J Transplant. 14(6):1417-1424.
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    A liver, heart, iliac vessel and two kidneys were recovered from a 39-year-old man who died of traumatic head injury and were transplanted into five recipients. The liver recipient 18 days posttransplantation presented with headache, ataxia and fever...
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  5. Serologic Survey for Exposure Following Fatal Balamuthia mandrillaris Infection
    Personal Author:
    Jackson, Brendan R.; Kucerova, Zuzana; Roy, Sharon L.; Aguirre, Glenda; Weiss, Joli; Sriram, Rama; Yoder, Jonathan; Foelber, Rebecca; Baty, Steven; Derado, Gordana; Stramer, Susan L.; Winkelman, Valerie; Visvesvara, Govinda S.;
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    Jan 24 2014
    Source:
    Parasitol Res. 113(4):1305-1311.
    Description:
    Granulomatous amebic encephalitis (GAE) from Balamuthia mandrillaris, a free-living ameba, has a case fatality rate exceeding 90% among recognized cases in the USA. In August 2010, a GAE cluster occurred following transplantation of infected organs f...
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