Decreased Levofloxacin Susceptibility in Haemophilus influenzae in Children, Hong Kong

Ho, Pak-Leung; Chow, Kin Hung; Mak, Gannon C.; Tsang, Kenneth W.; Lau, Yu Lung; Ho, Alex Y.; Lai, Eileen L.; Chiu, Susan S.

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Decreased Levofloxacin Susceptibility in Haemophilus influenzae in Children, Hong Kong

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Nov 2004
By Ho, Pak-Leung ; Chow, Kin Hung ; Mak, Gannon C. ; ...

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Ho, Pak-Leung ; Chow, Kin Hung ; Mak, Gannon C. ; Tsang, Kenneth W. ; Lau, Yu Lung ; Ho, Alex Y. ; Lai, Eileen L. ; Chiu, Susan S.
Description:

Among 563 strains of Haemophilus influenzae from young children in Hong Kong, 5 (0.9%) had decreased susceptibility to quinolones. The five strains had a Ser-84-Lys or Asp-88-Asn substitution in GyrA. Pulsed-field gel electrophoresis showed that the isolates are genetically diverse.
Subjects:

Anti-Bacterial Agents Anti‑infective Agents Carrier State Child Child, Preschool Dispatch Drug Resistance Drug Resistance, Bacterial Fluoroquinolone Haemophilus Influenza Haemophilus Influenzae Hong Kong Humans Infant Levofloxacin Microbial Nalidixic Acid Nasopharynx Ofloxacin Pulsed-field Gel Electrophoresis
Source:

Emerg Infect Dis. 10(11):1660-1962.
Document Type:

Journal Article
Volume:

10
Issue:

11
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:1306395ffdec2da9f26d6cbe8fcc8b27aa3842139ded2d91e19ba5386f326329
Download URL:

https://stacks.cdc.gov/view/cdc/14593/cdc_14593_DS1.pdf
File Type:

[PDF - 196.84 KB ]

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