Community-Acquired Klebsiella pneumoniae Bacteremia: Global Differences in Clinical Patterns

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Ko, Wen-Chien ; Paterson, David L. ; Sagnimeni, Anthanasia J. ; Hansen, Dennis S. ; Von Gottberg, Anne ; Mohapatra, Sunita ; Casellas, Jose Maria ; Goossens, Herman ; Mulazimoglu, Lutfiye ; Trenholme, Gordon ; Klugman, Keith P. ; McCormack, Joseph G. ; Yu, Victor L.
• Description:
  We initiated a worldwide collaborative study, including 455 episodes of bacteremia, to elucidate the clinical patterns of Klebsiella pneumoniae. Historically, community-acquired pneumonia has been consistently associated with K. pneumoniae. Only four cases of community-acquired bacteremic K. pneumoniae pneumonia were seen in the 2-year study period in the United States, Argentina, Europe, or Australia; none were in alcoholics. In contrast, 53 cases of bacteremic K. pneumoniae pneumonia were observed in South Africa and Taiwan, where an association with alcoholism persisted (p=0.007). Twenty-five cases of a distinctive syndrome consisting of K. pneumoniae bacteremia in conjunction with community-acquired liver abscess, meningitis, or endophthalmitis were observed. A distinctive form of K. pneumoniae infection, often causing liver abscess, was identified, almost exclusively in Taiwan.
• Subjects:
  Adolescent Adult Bacteremia Community-Acquired Infections Diagnosis, Differential Female Global Health Humans Klebsiella Infections Klebsiella Pneumoniae Male Middle Aged Pneumonia, Bacterial Prospective Studies Research Syndrome

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• Source:
  Emerg Infect Dis. 8(2):160-166.
• Document Type:
  Journal Article
• Place as Subject:
  South Africa ; Taiwan
• Location:
  Africa ; Asia
• Volume:
  8
• Issue:
  2
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:69ddab61823a02799ad779c75e9c25a572bd47892af6de857a0255023575740d
• Download URL:
  https://stacks.cdc.gov/view/cdc/13747/cdc_13747_DS1.pdf
• File Type:
  [PDF - 95.94 KB ]