Case of Extensively Drug-Resistant Shigella sonnei Infection, United States

Choi, Hosoon; Navarathna, Dhammika H.; Harston, Brennon L.; Hwang, Munok; Corona, Brandon; San Juan, Ma Rowen; Jinadatha, Chetan

doi:10.3201/eid2908.230411

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Case of Extensively Drug-Resistant Shigella sonnei Infection, United States

8 2023
By Choi, Hosoon ; Navarathna, Dhammika H. ; Harston, Brennon L. ; ...
http://dx.doi.org/10.3201/eid2908.230411
Source: Emerg Infect Dis. 2023; 29(8):1708-1711

[PDF-350.67 KB]

English

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Choi, Hosoon ; Navarathna, Dhammika H. ; Harston, Brennon L. ; Hwang, Munok ; Corona, Brandon ; ... More +

Choi, Hosoon ; Navarathna, Dhammika H. ; Harston, Brennon L. ; Hwang, Munok ; Corona, Brandon ; San Juan, Ma Rowen ; Jinadatha, Chetan Less -
Description:

We report extensively drug-resistant (XDR) Shigella sonnei infection in an immunocompromised patient in Texas, USA. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry failed to identify XDR Shigella, but whole-genome sequencing accurately characterized the strain. First-line antimicrobials are not effective against emerging XDR Shigella. Fosfomycin, carbapenems, and tigecycline are potential alternatives.
Subjects:

[+]

Anti-Bacterial Agents Anti-Infective Agents Antimicrobial Resistance Bacteria Case Of Extensively Drug-Resistant Shigella Sonnei Infection, United States Dysentery, Bacillary Enteric Infections Extensively Drug-resistant Shigella Humans Men Who Have Sex With Men Microbial Sensitivity Tests MSM Research Letter Sexually Transmitted Infections Shigella Shigella Sonnei United States Whole-genome Sequencing XDR Shigella
Source:

Emerg Infect Dis. 2023; 29(8):1708-1711
Pubmed ID:

37486233
Pubmed Central ID:

PMC10370867
Document Type:

Journal Article
Volume:

29
Issue:

8
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:1ed219fef022a929805ff558f827a9c4051c86630ac0fbf637da6528357a5ab7
Download URL:

https://stacks.cdc.gov/view/cdc/132626/cdc_132626_DS1.pdf
File Type:

23-0411.nxml

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