Case of Extensively Drug-Resistant Shigella sonnei Infection, United States

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Choi, Hosoon ; Navarathna, Dhammika H. ; Harston, Brennon L. ; Hwang, Munok ; Corona, Brandon ; San Juan, Ma Rowen ; Jinadatha, Chetan
• Description:
  We report extensively drug-resistant (XDR) Shigella sonnei infection in an immunocompromised patient in Texas, USA. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry failed to identify XDR Shigella, but whole-genome sequencing accurately characterized the strain. First-line antimicrobials are not effective against emerging XDR Shigella. Fosfomycin, carbapenems, and tigecycline are potential alternatives.
• Subjects:
  Anti-Bacterial Agents Anti-Infective Agents Antimicrobial Resistance Bacteria Case Of Extensively Drug-Resistant Shigella Sonnei Infection, United States Dysentery, Bacillary Enteric Infections Extensively Drug-resistant Shigella Humans Men Who Have Sex With Men Microbial Sensitivity Tests MSM Research Letter Sexually Transmitted Infections Shigella Shigella Sonnei United States Whole-genome Sequencing XDR Shigella

  More +
• Source:
  Emerg Infect Dis. 2023; 29(8):1708-1711
• Pubmed ID:
  37486233
• Pubmed Central ID:
  PMC10370867
• Document Type:
  Journal Article
• Volume:
  29
• Issue:
  8
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:1ed219fef022a929805ff558f827a9c4051c86630ac0fbf637da6528357a5ab7
• Download URL:
  https://stacks.cdc.gov/view/cdc/132626/cdc_132626_DS1.pdf
• File Type:
  [PDF - 350.67 KB ]