Detection of OXA-181 Carbapenemase in Shigella flexneri

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Dhabaan, Ghulam ; Jamal, Hassan ; Ouellette, Danielle ; Alexander, Sarah ; Arane, Karen ; Campigotto, Aaron ; Tadros, Manal ; Piché-Renaud, Pierre-Philippe
• Description:
  We report the detection of OXA-181 carbapenemase in an azithromycin-resistant Shigella spp. bacteria in an immunocompromised patient. The emergence of OXA-181 in Shigella spp. bacteria raises concerns about the global dissemination of carbapenem resistance in Enterobacterales and its implications for the treatment of infections caused by Shigella bacteria.
• Subjects:
  Anti-Bacterial Agents Azithromycin Bacterial Proteins Beta-Lactamases Drug Resistance, Bacterial Dysentery, Bacillary Humans Immunocompromised Host Male Microbial Sensitivity Tests Shigella Flexneri

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• Keywords:
  Antimicrobial Resistance Bacteria Beta-lactamases Canada Carbapenemase Enteric Infections India OXA-48 OXA-48-like OXA-181
• Source:
  Emerg Infect Dis. 2024; 30(5):1048-1050
• Pubmed ID:
  38666725
• Pubmed Central ID:
  PMC11060442
• Document Type:
  Journal Article
• Genre:
  Research Letter
• Volume:
  30
• Issue:
  5
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:17cc190f4381a41d743eab6e02c4eeffb2fa8438c84d182167b40985d0f11ab7
• Download URL:
  https://stacks.cdc.gov/view/cdc/154871/cdc_154871_DS1.pdf
• File Type:
  [PDF - 326.09 KB ]