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CDC Public Access

CDC Stacks Public Health Publications

Items in this collection are manuscripts and articles written by CDC or CDC-funded authors, and published in scholarly journals outside CDC. These items are available in compliance with the 2024 update of CDC-GA-2013-01 CDC Public Access to CDC-Funded Publications, available at: https://stacks.cdc.gov/view/cdc/159734.

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Showing 27581 - 27600 of 27880 results
  • The major histocompatibility complexrestricted response of recombinant inbred strains of mice to natural tick transmission of Borrelia burgdorferi
    The major histocompatibility complex-restricted response of recombinant inbred strains of mice to natural tick transmission of Borrelia burgdorferi
    Jan 1 1993 | J Exp Med. 177(1):9-17.
    The causative agent of Lyme disease, Borrelia burgdorferi, is transmitted by ticks of the Ixodes ricinus complex. In this study, we report the antibody response of recombinant inbred strains of mice of the H-2, b, d, and k haplotypes, infected with B. burgdorferi as a result of exposure to infected I. dammini. The patterns of antibody response assa ...
    Supporting Files Public Domain
  • Probability of Making A Successful Mine Escape While Wearing A SelfContained SelfRescuer
    Probability of Making A Successful Mine Escape While Wearing A Self-Contained Self-Rescuer
    Kovac, John G. ;
    Vaught, Charles
    Winter 1992
    A computer simulation has been developed to estimate the chances of a miner making a successful escape while wearing a SCSR. The model takes into account: (1) training in the use of SCSRs, (2) apparatus integrity, and (3) the oxygen cost of a mine escape. This Bureau of Mines report examines survival odds for a prototypical escape, and illustrates ...
    Public Domain
  • The findings of the Agency for Toxic Substances and Disease Registry Medical Waste Tracking Act report
    The findings of the Agency for Toxic Substances and Disease Registry Medical Waste Tracking Act report.
    Lichtveld, M Y ;
    Rodenbeck, S E
    Nov 1992 | Environ Health Perspect. 98:243-250.
    The Agency for Toxic Substances and Disease Registry (ATSDR) report "The Public Health Implications of Medical Waste: A Report to Congress" has been finalized and submitted to Congress. The report is a comprehensive review of all available data and information on the subject. Based on the data developed in the report, ATSDR concludes that the gener ...
    Supporting Files Public Domain
  • Biomarkers in Epidemiology Scientific Issues and Ethical Implications
    Biomarkers in Epidemiology: Scientific Issues and Ethical Implications
    Schulte, Paul A.
    1992/11/01 | Environ Health Perspect 1992 Nov; 98:143-147 | National Institute for Occupational Safety and Health (NIOSH)
    Biomarkers used in epidemiology were discussed with respect to scientific issues and ethical concerns. Currently used biomarkers were characterized by: the ability to detect xenobiotics at concentrations at the cellular and molecular level; the ability to detect earlier biologic changes presumptive of disease or disease risk; and to identify a deta ...
    Supporting Files Public Domain
  • Membrane protein sorting in the yeast secretory pathway evidence that the vacuole may be the default compartment
    Membrane protein sorting in the yeast secretory pathway: evidence that the vacuole may be the default compartment
    Oct 1992 | J Cell Biol. 119(1):69-83.
    The targeting signals of two yeast integral membrane dipeptidyl aminopeptidases (DPAPs), DPAP B and DPAP A, which reside in the vacuole and the Golgi apparatus, respectively, were analyzed. No single domain of DPAP B is required for delivery to the vacuolar membrane, because removal or replacement of either the cytoplasmic, transmembrane, or lumena ...
    Supporting Files
  • MPS1 and MPS2 novel yeast genes defining distinct steps of spindle pole body duplication
    MPS1 and MPS2: novel yeast genes defining distinct steps of spindle pole body duplication
    Aug 1991 | J Cell Biol. 114(4):745-754.
    It is crucial to the eucaryotic cell cycle that the centrosome undergo precise duplication to generate the two poles of the mitotic spindle. In the budding yeast Saccharomyces cerevisiae, centrosomal functions are provided by the spindle pole body (SPB), which is duplicated at the time of bud emergence in G1 of the cell cycle. Genetic control of th ...
    Supporting Files
  • Identification of sentinel health events as indicators of environmental contamination
    Identification of sentinel health events as indicators of environmental contamination.
    Rothwell, C J ;
    Hamilton, C B
    Aug 1991 | Environ Health Perspect. 94:261-263.
    The consensus process was applied to addressing a public health topic; this was a novel endeavor. The following question was addressed: What role, if any, should sentinel health events play in the decision-making process for identifying the effects of environmental exposure? The panel developed three levels of sentinel health events lists: those th ...
    Supporting Files Public Domain
  • Rapid Sampling of Products During Coal Mine Explosions
    Rapid Sampling of Products During Coal Mine Explosions
    Conti, Ronald S. ;
    Zlochower, Isaac A.
    02/01/1991 | Combust Sci and Technol 1991 Feb; 75(4-6):195-209
    This paper describes a U.S. Bureau of Mines investigation of large-scale coal dust explosions in an experimental mine using a high speed electro pneumatic mechanism for the rapid grab-sampling of gases and dusts. This technique enables the monitoring of pyrolysis and charring in fuel dust particles, and the collection of gaseous combustion products ...
    Public Domain
  • The potential of exposure biomarkers in epidemiologic studies of reproductive health
    The potential of exposure biomarkers in epidemiologic studies of reproductive health.
    Hogue, C J ;
    Brewster, M A
    Jan 1991 | Environ Health Perspect. 90:261-269.
    To further the development and application of exposure markers in field investigations in reproductive epidemiology, we have synthesized recent examinations of the issues surrounding exposure measurements in reproductive epidemiology. The specific goals of this paper are to define exposure biomarkers and explore their potential uses, particularly a ...
    Supporting Files Public Domain
  • Validation of Biological Markers for Quantitative Risk Assessment
    Validation of Biological Markers for Quantitative Risk Assessment
    Schulte, Paul A. ;
    Mazzuckelli, Lawrence F.
    1991/01/01 | Environ Health Perspect 1991 Jan; 90:239-246 | National Institute for Occupational Safety and Health (NIOSH)
    The evaluation of biological markers for quantitative risk assessment was discussed. The concept of validity included measurement validity, internal study validity, and external validity. Measurement validity can be defined as the extent to which a measurement means exactly what it claims to measure. Measurement validity can also be characterized a ...
    Supporting Files Public Domain
  • Possible Mechanism For Surface Vibrations Near Maxwell Hill West Virginia
    Possible Mechanism For Surface Vibrations Near Maxwell Hill, West Virginia
    Iannacchione, Anthony ;
    Mark, Christopher
    08/01/1990 | Bull Assoc Eng Geol 1990 Aug; 27(3):341-353
    Residents of Maxwell Hill, a suburb of Beckley, West Virginia, reported from January until March of 1988 a series of earth tremors. The tremors rattled dishes, and the noises associated with tremors were sometimes loud enough to wake people at night. These events were puzzling because Beckley is in an area of low seismic activity. Maxwell Hill is l ...
    Public Domain
  • Occupational Exposure of Workers to 13Butadiene
    Occupational Exposure of Workers to 1,3-Butadiene
    Fajen, John M. ;
    Roberts, Dennis R.
    1990/06/01 | Environ Health Perspect 1990 Jun; 86:11-18 | National Institute for Occupational Safety and Health (NIOSH)
    An investigation was conducted to examine the current extent of exposure data obtained for 1,3-butadiene (106990) and to provide recommendations for reducing potential exposures to 1,3-butadiene. The monitoring results from the present NIOSH investigation for the 1,3-butadiene industry revealed that full shift personal exposures for all job categor ...
    Supporting Files Public Domain
  • Environmental Epidemiologic Investigations in the StyreneButadiene Rubber Production Industry
    Environmental Epidemiologic Investigations in the Styrene-Butadiene Rubber Production Industry
    Lemen, Richard A. ;
    Meinhardt, Theodore J.
    1990/06/01 | Environ Health Perspect 1990 Jun; 86:103-106 | National Institute for Occupational Safety and Health (NIOSH)
    A review was provided of the current literature concerning cohort mortality studies of the styrene (100425) 1,3-butadiene (106990) industry. A detailed study was undertaken of the industry beginning in 1976 following the leukemia deaths of two men employed at adjacent styrene/butadiene rubber facilities in Texas. The facilities began production in ...
    Supporting Files Public Domain
  • Molecular cloning and characterization of the structural gene for the major ironregulated protein expressed by Neisseria gonorrhoeae
    Molecular cloning and characterization of the structural gene for the major iron-regulated protein expressed by Neisseria gonorrhoeae
    May 1 1990 | J Exp Med. 171(5):1535-1546.
    This report describes the cloning and sequencing of the major iron-regulated protein (termed Fbp) of Neisseria gonorrhoeae strain F62. Attempts to identify recombinants expressing the Fbp using specific antibody proved unsuccessful. Therefore, an alternative cloning strategy using oligonucleotide probes derived from NH2-terminal and tryptic fragmen ...
    Supporting Files Public Domain
  • Toxicity of styrene vapor in hepatocyte monolayers at low oxygen tensions
    Toxicity of styrene vapor in hepatocyte monolayers at low oxygen tensions.
    Costa, A K ;
    Trudell, J R
    Mar 1990 | Environ Health Perspect. 84:209-213.
    Hepatocyte monolayer cultures were exposed to 6000 ppm styrene vapor at 20%, 2%, or 1% O2 and assayed for signs of cell damage immediately following the 2-hr exposure and then 24 hr later. Oxygen concentrations were used that were previously shown to maximize lipid peroxidation and to predispose hepatocyte monolayers to chemical injury. The use of ...
    Supporting Files
  • MHC control of CD4 T cell subset activation
    MHC control of CD4+ T cell subset activation
    Dec 1 1989 | J Exp Med. 170(6):2135-2140.
    The present results demonstrate that CD4+ T cells activated in the primary in vivo response to antigen produce distinct patterns of cytokines depending upon the MHC class II haplotype of the responding mice. I-As mice were found to selectively activate IL-2/IFN-gamma-producing CD4+ T cells, whereas I-Ab mice exhibited selective activation of IL-4-p ...
    Supporting Files Public Domain
  • Regulation of chemoattractant receptor interaction with transducing proteins by organizational control in the plasma membrane of human neutrophils
    Regulation of chemoattractant receptor interaction with transducing proteins by organizational control in the plasma membrane of human neutrophils
    Dec 1989 | J Cell Biol. 109(6):2783-2790.
    Isolated purified plasma membrane domains from unstimulated human neutrophils were photoaffinity labeled with F-Met-Leu-Phe-N epsilon-(2-(p-azido-[125I]salicylamido)ethyl- 1,3'-dithiopropionyl)-Lys also referred to as FMLPL-SASD[125I]. Most of the photoaffinity-labeled N-formyl peptide receptors were found in light plasma membrane fraction (PM-L) w ...
    Supporting Files
  • Acidification of the lysosomelike vacuole and the vacuolar HATPase are deficient in two yeast mutants that fail to sort vacuolar proteins
    Acidification of the lysosome-like vacuole and the vacuolar H+-ATPase are deficient in two yeast mutants that fail to sort vacuolar proteins
    Jul 1989 | J Cell Biol. 109(1):93-100.
    Organelle acidification plays a demonstrable role in intracellular protein processing, transport, and sorting in animal cells. We investigated the relationship between acidification and protein sorting in yeast by treating yeast cells with ammonium chloride and found that this lysosomotropic agent caused the mislocalization of a substantial fractio ...
    Supporting Files
  • Characterization of synapsin I fragments produced by cysteinespecific cleavage a study of their interactions with Factin
    Characterization of synapsin I fragments produced by cysteine-specific cleavage: a study of their interactions with F-actin
    May 1989 | J Cell Biol. 108(5):1841-1849.
    Synapsin I is a neuron-specific phosphoprotein that is concentrated in the presynaptic nerve terminal in association with the cytoplasmic surface of synaptic vesicles. It has been demonstrated to bundle F-actin in a phosphorylation-dependent manner in vitro, a property consistent with its proposed role in linking synaptic vesicles to the cytoskelet ...
    Supporting Files
  • Epidemiological and clinical features of 1149 persons with Lyme disease identified by laboratorybased surveillance in Connecticut
    Epidemiological and clinical features of 1,149 persons with Lyme disease identified by laboratory-based surveillance in Connecticut.
    Petersen, L. R. ;
    Sweeney, A. H.
    1989 May-Jun | Yale J Biol Med. 62(3):253-262.
    Laboratory-based surveillance of Lyme disease in Connecticut during 1984 and 1985 identified 3,098 persons with suspected Lyme disease; 1,149 were defined as cases. Lyme disease incidence in Connecticut towns ranged from none to 1,407 cases per 100,000 population in 1985. A comparison of 1985 data with data from 1977 epidemiologic studies indicated ...
    Supporting Files Public Domain
27581 - 27600 / 27880