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Showing 2521 - 2540 of 82972 results
  • Aging Influence on Pulmonary and Systemic Inflammation and Neural Metabolomics Arising from Pulmonary MultiWalled Carbon Nanotube Exposure in Apolipoprotein EDeficient and C57BL6 Female Mice
    Aging Influence on Pulmonary and Systemic Inflammation and Neural Metabolomics Arising from Pulmonary Multi-Walled Carbon Nanotube Exposure in Apolipoprotein E-Deficient and C57BL/6 Female Mice
    Begay JG ;
    Campen MJ
    2023/03/21 | National Institute for Occupational Safety and Health (NIOSH)
    Objective: Environmental exposures exacerbate age-related pathologies, such as cardiovascular and neurodegenerative diseases. Nanoparticulates, and specifically carbon nanomaterials, are a fast-growing contributor to the category of inhalable pollutants, whose risks to health are only now being unraveled. The current study assessed the exacerbating ...
  • Genetic Liability Exposure Severity and PostTraumatic Stress Disorder Predict Cognitive Impairment in World Trade Center Responders
    Genetic Liability, Exposure Severity, and Post-Traumatic Stress Disorder Predict Cognitive Impairment in World Trade Center Responders
    Carr MA ;
    Clouston SAP
    2023/03/21 | National Institute for Occupational Safety and Health (NIOSH)
    Background: There is a high incidence of cognitive impairment among World Trade Center (WTC) responders, comorbid with post-traumatic stress disorder (PTSD). Yet, it remains unknown whether genetic liability for Alzheimer's disease, PTSD, educational attainment, or for a combination of these phenotypes, is associated with cognitive impairment in th ...
  • A Toxicological Study of the Respirable Coal Mine Dust Assessment of Different Dust Sources Within the Same Mine
    A Toxicological Study of the Respirable Coal Mine Dust: Assessment of Different Dust Sources Within the Same Mine
    Camacho A ;
    Das M
    2023/03/18 | National Institute for Occupational Safety and Health (NIOSH)
    Respirable coal mine dust (RCMD) exposure is one of the utmost health hazards to the mining community causing various health issues, including coal worker pneumoconiosis (CWP). Considering multiple potential sources of RCMD having different physicochemical properties within the same mine suggests a wide range of health impacts that have not yet bee ...
  • Correlation Between Graphitic Carbon and Elemental Carbon in Diesel Particulate Matter in Workplace Atmospheres (Dataset)
    National Institute for Occupational Safety and Health
    2023/03/17 | National Institute for Occupational Safety and Health (NIOSH)
    We investigated the suitability of graphitic carbon (GC) content of diesel particulate matter (DPM), measured using Raman spectroscopy, as a surrogate measure of elemental carbon (EC), determined by thermal optical analysis. Raman spectra in the range of 800-1800 cm-1 (including the D mode at approx. 1322 cm-1 and the G mode at approx. 1595 cm-1) w ...
    Dataset Public Domain
  • Local Health Department Engagement with Workplaces During the COVID19 Pandemic Examining Barriers of and Facilitators to Outbreak Investigation and Mitigation
    Local Health Department Engagement with Workplaces During the COVID-19 Pandemic – Examining Barriers of and Facilitators to Outbreak Investigation and Mitigation
    Bonney T ;
    Grant, Michael P.
    2023/03/17 | National Institute for Occupational Safety and Health (NIOSH)
    Objectives: To document local health department (LHD) COVID-19 prevention or mitigation activities at workplaces in the United States and identify facilitators for and barriers to these efforts. Methods: We conducted a web-based, cross-sectional national probability survey of United States LHDs (n = 181 unweighted; n = 2,284 weighted) from January ...
    Public Domain
  • NanoSpotTM Collector for Aerosol Sample Collection for Direct Microscopy and Spectroscopy Analysis (Dataset)
    National Institute for Occupational Safety and Health
    2023/03/17 | National Institute for Occupational Safety and Health (NIOSH)
    We describe design and characterization of an aerosol NanoSpotTM collector, designed for collection of airborne particles on a microscopy substrate for direct electron microscopy, optical microscopy, and laser spectroscopy analysis. The collector implements a water-based, laminar-flow, condensation growth technique, followed by impaction onto an op ...
    Dataset Public Domain
  • Line of Duty Death Report Report Slides 51YearOld Firefighter Suffers a Sudden Cardiac Event and Crashes Engine While Responding to a Residential Structure Fire West Virginia
    Line of Duty Death Report Report Slides: 51-Year-Old Firefighter Suffers a Sudden Cardiac Event and Crashes Engine While Responding to a Residential Structure Fire – West Virginia
    National Institute for Occupational Safety and Health  ...
    2023/03/16 | Fire Fighter Fatality Investigation and Prevention Program (FFFIPP)
    On January 11, 2020, a 51-year-old male volunteer firefighter died while responding to a mutual aid call for a residential structure fire. While driving the department's engine to the fire scene, the firefighter suffered a sudden cardiac event causing him to lose control of the apparatus approximately ½ mile from the structure fire. At approximatel ...
    Public Domain
  • Warehouse Worker Dies When Material Falling Off of Pallet Strikes Him California
    Warehouse Worker Dies When Material Falling Off of Pallet Strikes Him — California
    Chan, Jacqueline ;
    Kleinmann, Robert L. P.
    2023/03/15 | Fatality Assessment and Control Evaluation Reports (FACE)
    On May 13, 2022, a 39-year-old male warehouse worker was acting as a 'spotter' and assisting a forklift operator who was moving pallets of cased bottled water near the end of the night shift. The pallets were shrink wrapped, double stacked, and combined stood about 9 ½ feet high. As the forklift operator tried to remove the top pallet, the forks ma ...
  • The World Trade Center Health Program Smoking Cessation
    The World Trade Center Health Program: Smoking Cessation
    Calvert, Geoffrey M. ;
    Lilly, Gerald
    2023/03/15 | National Institute for Occupational Safety and Health (NIOSH)
    Cigarette smoking can cause and/or worsen a variety of health conditions. The U.S. Preventive Services Task Force (USPSTF) recommends that smoking cessation services be offered to all adults who currently smoke, and governmental and non-governmental professional organizations support providing these interventions to patients who smoke. The World Tr ...
    Public Domain
  • Developmental Programming Adipose DepotSpecific Regulation of NonCoding RNAs and Their Relation to Coding RNA Expression in Prenatal Testosterone and Prenatal Bisphenola Treated Female Sheep
    Developmental Programming: Adipose Depot-Specific Regulation of Non-Coding RNAs and Their Relation to Coding RNA Expression in Prenatal Testosterone and Prenatal Bisphenol-a -Treated Female Sheep
    Bakulski K ;
    Dou J
    2023/03/15 | National Institute for Occupational Safety and Health (NIOSH)
    Inappropriate developmental exposure to steroids is linked to metabolic disorders. Prenatal testosterone excess or bisphenol A (BPA, an environmental estrogen mimic) leads to insulin resistance and adipocyte disruptions in female lambs. Adipocytes are key regulators of insulin sensitivity. Metabolic tissue-specific differences in insulin sensitivit ...
  • Sex Differences in the Th2 LungBrain Axis Response to Aspergillus Versicolor Inhalation in C57BL6J Mice
    Sex Differences in the Th2 Lung-Brain Axis Response to Aspergillus Versicolor Inhalation in C57BL/6J Mice
    Ahmed, C. ;
    Beezhold, Donald H.
    2023/03/15 | National Institute for Occupational Safety and Health (NIOSH)
    Alzheimer's disease (AD) is a devastating form of dementia that includes a dysregulated microglial phenotype and maladaptive immune cell trafficking. Yet the identity of environmental exposures that are culpable in this disruption, and in peripheral immune responses regulating the brain remain poorly understood. Aspergillus versicolor is a common f ...
    Public Domain
  • Characterization and Toxicity Assessment of Aerosolized Particles Generated During Cutting of Carbon NanotubesEmbedded Concrete
    Characterization and Toxicity Assessment of Aerosolized Particles Generated During Cutting of Carbon Nanotubes-Embedded Concrete
    Afshari A ;
    Erdely A
    2023/03/14 | National Institute for Occupational Safety and Health (NIOSH)
    Carbon nanotube (CNT) as a reinforcement enhances durability and performance of concrete composites. Exposure to some forms of CNT is known to cause adverse pathological outcomes. To understand potential toxicity arising from use of CNT-enabled concrete composites as it goes through various occupational life cycle stages, we evaluated 1) the physic ...
    Public Domain
  • Lung Response to Coal Dust and Crystalline Silica Exposure in Rats
    Lung Response to Coal Dust and Crystalline Silica Exposure in Rats
    Beck T ;
    Joseph P
    2023/03/14 | Mining Publications
    The role of crystalline silica in the re-emergence of coal workers pneumoconiosis reported in certain U.S. Appalachian states was investigated by employing an experimental rat model of lung toxicity. A computer-controlled, automated aerosol generation system was custom-built and employed to generate aerosols containing crystalline silica (Min-U-Sil ...
    Public Domain
  • Lung Toxicity in Rats After Inhalation of Aerosols Generated During Thermal Spray Coating Using Different Consumable Materials
    Lung Toxicity in Rats After Inhalation of Aerosols Generated During Thermal Spray Coating Using Different Consumable Materials
    Afshari A ;
    Andrews R
    2023/03/14 | National Institute for Occupational Safety and Health (NIOSH)
    Thermal spray coating (TSC) is an emerging industrial process in which molten metal is sprayed at a high velocity onto a surface as a protective coating. Little is known about the physical and chemical properties of the particles generated and the potential health effects associated with exposure to TSC aerosols. A computer controlled TSC generator ...
    Public Domain
  • In Vivo Toxicity Comparison of Surrogate Metal Oxide Mixtures from Welding Fumes
    In Vivo Toxicity Comparison of Surrogate Metal Oxide Mixtures from Welding Fumes
    Antonini JM ;
    Betler E
    2023/03/14 | National Institute for Occupational Safety and Health (NIOSH)
    Occupational exposure to welding fumes (WF), a Group 1 carcinogen (carcinogenic to humans), is a complex metal mixture commonly composed of iron (Fe), nickel (Ni), and chromium (Cr). The objective was to assess the acute in vivo toxicity of different metal oxide combinations (Cr + Ni; Fe + Ni; Fe + Cr; Fe + Cr + Ni), in proportions representing tho ...
    Public Domain
  • Dissolution of Inorganic Lead Pb Compounds in Synthetic Sweat to Assess Risk of Dermal Exposure
    Dissolution of Inorganic Lead (Pb) Compounds in Synthetic Sweat to Assess Risk of Dermal Exposure
    Hudson N ;
    Maier A
    2023/03/14 | National Institute for Occupational Safety and Health (NIOSH)
    It is estimated that over 4.53x108 kg of inorganic lead (iPb) compounds were manufactured in the U.S. in 2020. Over 1.4 million U.S. workers have dermal exposures to iPb compounds in several industries with loading of iPb on hands varying widely (0.005-16.1 µg/cm2). In vitro skin studies suggest that dermal exposures to iPb could increase blood lea ...
    Public Domain
  • Aberration of Corticothalamic Brain Regions in Rats Exposed to Welding Fumes
    Aberration of Corticothalamic Brain Regions in Rats Exposed to Welding Fumes
    Antonini JM ;
    Lin GX
    2023/03/14 | National Institute for Occupational Safety and Health (NIOSH)
    The potential for developing Parkinson's disease (PD)-like neurological dysfunction following occupational exposure to welding fumes (WF) is an emerging concern. Manganese (Mn) in welding consumables is suspected to cause the neurological deficits seen in welders. Indeed, we have shown that Mn-containing WF causes dopaminergic neurotoxicity in rats ...
    Public Domain
  • Toxicity and Transcriptome Comparisons of Different Firefighting Foam Exposures in Human Renal Proximal Tubule Epithelial Cells
    Toxicity and Transcriptome Comparisons of Different Firefighting Foam Exposures in Human Renal Proximal Tubule Epithelial Cells
    Beitel S ;
    Burgess J
    2023/03/14 | National Institute for Occupational Safety and Health (NIOSH)
    Firefighters have long used Military Specification aqueous film forming foams (AFFF), containing complex mixtures of per- and polyfluorinated alkyl substances (PFAS), to extinguish liquid fuel fires. Chronic disease concerns following AFFF exposure have arisen in the fire service based on elevated PFAS levels with long half lives in firefighter ser ...
    Public Domain
  • Acute Pulmonary Response and Lung Burden Following Solid Surface Composite Dust Inhalation
    Acute Pulmonary Response and Lung Burden Following Solid Surface Composite Dust Inhalation
    Battelli, L. A. ;
    Friend, S. A.
    2023/03/14 | National Institute for Occupational Safety and Health (NIOSH)
    Pulmonary exposure to emissions from manipulating solid surface composite (SSC) materials with power tools has been associated with adverse health effects in humans and laboratory animals. Previous in vitro and in vivo investigations of SSC toxicity have been limited by particle delivery methods that do not fully recapitulate the workplace environm ...
    Public Domain
  • Evaluating Exposure Hazards in Historical Collections
    Evaluating Exposure Hazards in Historical Collections
    Burnell, Kenneth ;
    Cusack-McVeigh, H.
    2023/03/14 | National Institute for Occupational Safety and Health (NIOSH)
    Museum collections and exhibit spaces often contain health hazards as a result of historic preservation treatments and environmental conditions within the buildings. These hazards present dangers to the health and safety of those charged with their care and display. For example, individuals who encounter treated artifacts are at risk of exposure to ...
2521 - 2540 / 82972