Dietary Inflammatory Potential and Bone Outcomes in Midwestern Post-Menopausal Women

Details

• Personal Author:
  Bilek LD ; Graeff-Armas L ; Hans D ; Hanson C ; Hébert JR ; Jackson MK ; Lyden ER ; Ma J ; Mack LR ; Poole JA ; Price S ; Waltman NL
• Description:
  Little is known about the inflammatory potential of diet and its relation to bone health. This cross-sectional study examined the association between the inflammatory potential of diet and bone-related outcomes in midwestern, post-menopausal women enrolled in the Heartland Osteoporosis Prevention Study (HOPS) randomized controlled trial. Dietary intake from the HOPS cohort was used to calculate Dietary Inflammatory Index (DII®) scores, which were energy-adjusted (E-DIITM) and analyzed by quartile. The association between E-DII and lumbar and hip bone mineral density (BMD) and lumbar trabecular bone scores (TBS; bone structure) was assessed using ANCOVA, with pairwise comparison to adjust for relevant confounders (age, education, race/ethnicity, smoking history, family history of osteoporosis/osteopenia, BMI, physical activity, and calcium intake). The cohort included 272 women, who were predominately white (89%), educated (78% with college degree or higher), with a mean BMI of 27 kg/m2, age of 55 years, and E-DII score of -2.0 +/- 1.9 (more anti-inflammatory). After adjustment, E-DII score was not significantly associated with lumbar spine BMD (p = 0.53), hip BMD (p = 0.29), or TBS at any lumbar location (p > 0.05). Future studies should examine the longitudinal impact of E-DII scores and bone health in larger, more diverse cohorts. [Description provided by NIOSH]
• Subjects:
  Occupational Health Safety Women
• Keywords:
  Author Keywords: Dietary Inflammatory Index Bone Disorders Bone Mineral Density Cross Sectional Studies Dietary Effects Hormone Activity Nutrition Post-menopausal Women Trabecular Bone Scores
• ISSN:
  2072-6643
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Nebraska ; OSHA Region 4 ; OSHA Region 7 ; South Carolina
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  15
• Issue:
  19
• NIOSHTIC Number:
  nn:20069682
• Citation:
  Nutrients 2023 Oct; 15(19):4277
• Contact Point Address:
  Corrine Hanson, Medical Nutrition, Department of Medical Sciences, College of Allied Health Professions, University of Nebraska Medical Center, Omaha, NE 68198, USA
• Email:
  ckhanson@unmc.edu
• Federal Fiscal Year:
  2024
• NORA Priority Area:
  Agriculture, Forestry and Fishing
• Performing Organization:
  University of Nebraska Medical Center
• Peer Reviewed:
  True
• Start Date:
  20210901
• Source Full Name:
  Nutrients
• End Date:
  20250831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:c76e1af5b0ef16b16553438ab353bac1ebecc984bde9da37239d088d1551aab491bde90a53fc14452baa1980619b20f67740289e515a57ce8a16450535f31577
• Download URL:
  https://stacks.cdc.gov/view/cdc/208061/cdc_208061_DS1.pdf
• File Type:
  [PDF - 905.45 KB ]