Post-Traumatic Stress Disorder and Risk of First-Time and Repeated Opioid-Related Hospitalizations Among World Trade Center Health Registry Enrollees

Details

• Personal Author:
  Garrey SK ; Li J ; Locke S ; Pollari C ; Takemoto E
• Description:
  In 2021, and average of 220 deaths from opioid-related overdoses occurred daily in the US. Recent evidence suggests there is an association between post-traumatic stress disorder (PTSD) and increased opioid misuse, while little is known about opioid-related hospitalizations. This study used data from the World Trade Center Health Registry (WTCHR), a longitudinal cohort consisting of individuals directly exposed to the September 11th terrorist attacks with a high prevalence of resulting PTSD (3.8-29.6%). We linked WTCHR data to New York State hospitalization data to examine the question: do opioid-related hospitalizations (first time and repeated) differ by PTSD status. In a study sample of 37,968 adults, 145 experienced at least one episode of opioid-related hospitalization and 64 had repeated episodes during the study period. We found that in the 13-years post-9/11, individuals with PTSD had a significantly higher risk of a first-time opioid-related hospitalization (Hazard Ratio: 3.6, 95% CI: 2.7, 5.0) and repeated opioid-related hospitalizations (Hazard Ratio: 3.9, 95% CI: 2.7, 5.8) than those who did not have PTSD. Improved treatment of and increased screenings for PTSD may reduce the likelihood of opioid misuse in this population and consequently overdoses, hospitalizations, and healthcare costs. [Description provided by NIOSH]
• Subjects:
  Mental Health Nervous System Occupational Health Safety September 11 Terrorist Attacks
• Keywords:
  9/11 Author Keywords: PTSD Health Care Hospitalization Mental Health Opioids Opioid Use Disorder Post-traumatic Stress Disorder PTSD Substance Misuse World Trade Center World Trade Center Disaster WTC

  More +
• ISSN:
  0165-1781
• Document Type:
  Text
• Funding:
  Cooperative Agreement
• Genre:
  Journal Article
• Place as Subject:
  New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  328
• NIOSHTIC Number:
  nn:20069006
• Citation:
  Psychiatry Res 2023 Oct; 328:115462
• Contact Point Address:
  Jiehui Li, New York City Department of Health and Mental Hygiene, World Trade Center Health Registry, 42-09 28th Street, CN-6W, Long Island City, NY 11101, United States
• Email:
  jli3@health.nyc.gov
• Federal Fiscal Year:
  2024
• Performing Organization:
  New York City Health/Mental Hygiene
• Peer Reviewed:
  True
• Start Date:
  20090430
• Source Full Name:
  Psychiatry Research
• End Date:
  20260630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:d202d604f378de5e06e7d684afe430e09a9dd3391881485c8b546fde76cc9a80c0add9697eeb2f0a2086fb5bb4099b1ff2f364086b157055f39785089fe5b8fa
• Download URL:
  https://stacks.cdc.gov/view/cdc/207562/cdc_207562_DS1.pdf
• File Type:
  [PDF - 419.54 KB ]