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Emerging Infectious Diseases
Emerging Infectious Diseases (EID) is a peer-reviewed, monthly journal published by the Centers for Disease Control and Prevention (CDC). It offers the latest scientific information on emerging infectious diseases and trends. Emerging Infectious Diseases is freely available to the public as Diamond Open Access. For more on EID, visit https://wwwnc.cdc.gov/eid.
Two Canadian urban areas received travelers with severe acute respiratory syndrome (SARS) before the World Health Organization issued its alert. By July 2003, Vancouver had identified 5 cases (4 imported); Toronto reported 247 cases (3 imported) and 43 deaths. Baseline preparedness for pandemic threats may account for the absence of sustained trans
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Supporting FilesPublic Domain
Skowronski, D. M., Petric, M., Daly, P., Parker, R. A., Bryce, E., Doyle, P. W., Noble, M. A., Roscoe, D. L., Tomblin, J., Yang, T. C., Krajden, M., Patrick, D. M., Pourbohloul, B., Goh, S. H., Bowie, W. R., Booth, T. F., Tweed, S. A., Perry, T. L., McGeer, A., & Brunham, R. C. (2006). Coordinated Response to SARS, Vancouver, Canada. https://stacks.cdc.gov/view/cdc/15882
Skowronski, Danuta M., Martin Petric, Patricia Daly, Robert A. Parker, Elizabeth Bryce, Patrick W. Doyle, and Michael A. Noble, et al.. Coordinated Response to SARS, Vancouver, Canada. 2006. https://stacks.cdc.gov/view/cdc/15882.
The World Health Organization's recommended pandemic influenza interventions, based on limited data, vary by transmission pattern, pandemic phase, and illness severity and extent. In the pandemic alert period, recommendations include isolation of patients and quarantine of contacts, accompanied by antiviral therapy. During the pandemic period, the
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Supporting FilesPublic Domain
World Health Organization Writing Group (2006). Nonpharmaceutical Interventions for Pandemic Influenza, National and Community Measures. https://stacks.cdc.gov/view/cdc/16126
World Health Organization Writing Group. Nonpharmaceutical Interventions for Pandemic Influenza, National and Community Measures. 2006. https://stacks.cdc.gov/view/cdc/16126.
World Health Organization Writing Group Nonpharmaceutical Interventions for Pandemic Influenza, National and Community Measures. 2006, Stacks. https://stacks.cdc.gov/view/cdc/16126.
The threat of a human influenza pandemic has greatly increased over the past several years with the emergence of highly virulent avian influenza viruses, notably H5N1 viruses, which have infected humans in several Asian and European countries. Previous influenza pandemics have arrived with little or no warning, but the current widespread circulatio
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Current vaccine strategies against influenza focus on generating robust antibody responses. Because of the high degree of antigenic drift among circulating influenza strains over the course of a year, vaccine strains must be reformulated specifically for each influenza season. The time delay from isolating the pandemic strain to large-scale vaccine
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Supporting FilesPublic Domain
Thomas, P. G., Keating, R., Hulse-Post, D. J., & Doherty, P. C. (2006). Cell-mediated Protection in Influenza Infection. https://stacks.cdc.gov/view/cdc/16097
Thomas, Paul G., Rachael Keating, Diane J. Hulse-Post, and Peter C. Doherty. Cell-mediated Protection in Influenza Infection. 2006. https://stacks.cdc.gov/view/cdc/16097.
Given the potential for laboratory-associated severe acute respiratory syndrome-associated coronavirus (SARS-CoV) infections, we must know which cell lines are susceptible to the virus. We investigated 21 cell lines routinely used for virus isolation or research. After infection with SARS-CoV, cells were observed for cytopathic effects, and quantit
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Supporting FilesPublic Domain
Kaye, M., Druce, J., Tran, T., Kostecki, R., Chibo, D., Morris, J., Catton, M., & Birch, C. (2006). SARS–associated Coronavirus Replication in Cell Lines. https://stacks.cdc.gov/view/cdc/15916
Kaye, Matthew, Julian Druce, Thomas Tran, Renata Kostecki, Doris Chibo, Jessica Morris, Mike Catton, and Chris Birch. SARS–associated Coronavirus Replication in Cell Lines. 2006. https://stacks.cdc.gov/view/cdc/15916.
Since global availability of vaccine and antiviral agents against influenza caused by novel human subtypes is insufficient, the World Health Organization (WHO) recommends non-pharmaceutical public health interventions to contain infection, delay spread, and reduce the impact of pandemic disease. Virus transmission characteristics will not be comple
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Supporting FilesPublic Domain
World Health Organization Writing Group (2006). Nonpharmaceutical Interventions for Pandemic Influenza, International Measures. Emerg Infect Dis, 12(1). https://stacks.cdc.gov/view/cdc/16125
World Health Organization Writing Group. "Nonpharmaceutical Interventions for Pandemic Influenza, International Measures." Emerg Infect Dis 12, no. 1 (2006). https://stacks.cdc.gov/view/cdc/16125.
World Health Organization Writing Group "Nonpharmaceutical Interventions for Pandemic Influenza, International Measures." Emerg Infect Dis, vol. 12, no. 1, 2006. Stacks. https://stacks.cdc.gov/view/cdc/16125.
We evaluated titers of homotypic and heterotypic neutralizing antibodies (NAbs) to Andes and Sin Nombre hantaviruses in plasma samples from 20 patients from Chile and the United States. All but 1 patient had high titers of NAb. None of the plasma samples showed high titers against the heterologous virus.
Supporting FilesPublic Domain
Valdivieso, F., Vial, P., Ferres, M., Ye, C., Goade, D., Cuiza, A., & Hjelle, B. (2006). Neutralizing Antibodies in Survivors of Sin Nombre and Andes Hantavirus Infection. Emerging Infectious Diseases, 12(1). https://doi.org/10.3201/eid1201.050930
Valdivieso, Francisca, Pablo Vial, Marcela Ferres, Chunyan Ye, Diane Goade, Analia Cuiza, and Brian Hjelle. "Neutralizing Antibodies in Survivors of Sin Nombre and Andes Hantavirus Infection." Emerging Infectious Diseases 12, no. 1 (2006). https://doi.org/10.3201/eid1201.050930.
Valdivieso, Francisca, et al. "Neutralizing Antibodies in Survivors of Sin Nombre and Andes Hantavirus Infection." Emerging Infectious Diseases, vol. 12, no. 1, 2006. Stacks. https://doi.org/10.3201/eid1201.050930.
The "Spanish" influenza pandemic of 1918-1919, which caused approximately 50 million deaths worldwide, remains an ominous warning to public health. Many questions about its origins, its unusual epidemiologic features, and the basis of its pathogenicity remain unanswered. The public health implications of the pandemic therefore remain in doubt even
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Three worldwide (pandemic) outbreaks of influenza occurred in the 20th century: in 1918, 1957, and 1968. The latter 2 were in the era of modern virology and most thoroughly characterized. All 3 have been informally identified by their presumed sites of origin as Spanish, Asian, and Hong Kong influenza, respectively. They are now known to represent
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We compared strategies for stock piling neuraminidase inhibitors to treat and prevent influenza in Singapore. Cost-benefit and cost-effectiveness analyses, with Monte Carlo simulations, were used to determine economic outcomes. A pandemic in a population of 4.2 million would result in an estimated 525-1,775 deaths, 10,700-38,600 hospitalization day
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Supporting FilesPublic Domain
Lee, V. J., Phua, K. H., Chen, M. I., Chow, A., Ma, S., Goh, K. T., & Leo, Y. S. (2006). Economics of Neuraminidase Inhibitor Stockpiling for Pandemic Influenza, Singapore. https://stacks.cdc.gov/view/cdc/15928
Lee, Vernon J., Kai Hong Phua, Mark I. Chen, Angela Chow, Stefan Ma, Kee Tai Goh, and Yee Sin Leo. Economics of Neuraminidase Inhibitor Stockpiling for Pandemic Influenza, Singapore. 2006. https://stacks.cdc.gov/view/cdc/15928.
Lee, Vernon J., et al. Economics of Neuraminidase Inhibitor Stockpiling for Pandemic Influenza, Singapore. 2006, Stacks. https://stacks.cdc.gov/view/cdc/15928.
While measures such as closing schools and social distancing may slow the effects of pandemic influenza, only vaccines and antiviral drugs are clearly efficacious in preventing infection or treating illness. Unless the pandemic strain closely resembles one already recognized, vaccine will not be available early. However, studies can be conducted be
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In early 1976, the novel A/New Jersey/76 (Hsw1N1) influenza virus caused severe respiratory illness in 13 soldiers with 1 death at Fort Dix, New Jersey. Since A/New Jersey was similar to the 1918-1919 pandemic virus, rapid outbreak assessment and enhanced surveillance were initiated. A/New Jersey virus was detected only from January 19 to February
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Supporting FilesPublic Domain
Gaydos, J. C., Top, F. H., Hodder, R. A., & Russell, P. K. (2006). Swine Influenza A Outbreak, Fort Dix, New Jersey, 1976. https://stacks.cdc.gov/view/cdc/16039
Gaydos, Joel C., Franklin H. Top, Richard A. Hodder, and Philip K. Russell. Swine Influenza A Outbreak, Fort Dix, New Jersey, 1976. 2006. https://stacks.cdc.gov/view/cdc/16039.
Massoudi, Mehran S.. Behind the Mask: How the World Survived SARS, the First Epidemic of the 21st Century. 2005. https://stacks.cdc.gov/view/cdc/16066.
Massoudi, Mehran S. Behind the Mask: How the World Survived SARS, the First Epidemic of the 21st Century. 2005, Stacks. https://stacks.cdc.gov/view/cdc/16066.
Novais, C., Coque, T. M., Boerlin, P., Herrero, I., Moreno, M. A., Dominguez, L., & Peixe, L. (2005). Vancomycin-resistant Enterococcus faecium Clone in Swine, Europe. https://stacks.cdc.gov/view/cdc/15991
Novais, Carla, Teresa M. Coque, Patrick Boerlin, Inmaculada Herrero, Miguel A. Moreno, Lucas Dominguez, and Luísa Peixe. Vancomycin-resistant Enterococcus faecium Clone in Swine, Europe. 2005. https://stacks.cdc.gov/view/cdc/15991.
Zhang, Y. Z., Xiong, C. L., Xiao, D. L., Jiang, R. J., Wang, Z. X., Zhang, L. Z., & Fu, Z. F. (2005). Human Rabies in China. https://stacks.cdc.gov/view/cdc/15684
Zhang, Yong-Zhen, Cheng-Long Xiong, Dong-Lou Xiao, Ren-Jie Jiang, Zhao-Xiao Wang, Ling-Zhu Zhang, and Zhen F. Fu. Human Rabies in China. 2005. https://stacks.cdc.gov/view/cdc/15684.
Surveillance for Nipah virus (NV) was conducted in Thailand's bat population. Immunoglobulin G antibodies to NV were detected with enzyme immunoassay in 82 of 1,304 bats. NV RNA was found in bat saliva and urine. These data suggest the persistence of NV infection in Thai bats.
Supporting FilesPublic Domain
Wacharapluesadee, S., Lumlertdacha, B., Boongird, K., Wanghongsa, S., Chanhome, L., Rollin, P., Stockton, P., Rupprecht, C. E., Ksiazek, T. G., & Hemachudha, T. (2005). Bat Nipah Virus, Thailand. https://stacks.cdc.gov/view/cdc/7885
Wacharapluesadee, Supaporn, Boonlert Lumlertdacha, Kalyanee Boongird, Sawai Wanghongsa, Lawan Chanhome, Pierre Rollin, Patrick Stockton, Charles E. Rupprecht, Thomas G. Ksiazek, and Thiravat Hemachudha. Bat Nipah Virus, Thailand. 2005. https://stacks.cdc.gov/view/cdc/7885.
We identified a Bartonella quintana strain by polymerase chain reaction amplification, cloning, and sequencing of DNA extracted from lysed erythrocytes and cultured colonies grown from peripheral blood collected from a captive-bred cynomolgus monkey (Macaca fascicularis). This report describes naturally acquired B. quintana infection in a nonhuman
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Supporting FilesPublic Domain
O'Rourke, L. G., Pitulle, C., Hegarty, B. C., Kraycirik, S., Killary, K. A., Grosenstein, P., Brown, J. W., & Breitschwerdt, E. B. (2005). Bartonella quintana in Cynomolgus Monkey (Macaca fascicularis). https://stacks.cdc.gov/view/cdc/15592
O'Rourke, Laurie G., Christian Pitulle, Barbara C. Hegarty, Sharon Kraycirik, Karen A. Killary, Paul Grosenstein, James W. Brown, and Edward B. Breitschwerdt. Bartonella quintana in Cynomolgus Monkey (Macaca fascicularis). 2005. https://stacks.cdc.gov/view/cdc/15592.
We reviewed medical records of 238 hospitalized patients with Escherichia coli O157:H7 diarrhea to identify risk factors for progression to diarrhea-associated hemolytic uremic syndrome (HUS). Data indicated that young age, long duration of diarrhea, elevated leukocyte count, and proteinuria were associated with HUS.
Supporting FilesPublic Domain
Tserenpuntsag, B., Chang, H. G., Smith, P. F., & Morse, D. L. (2005). Hemolytic Uremic Syndrome Risk and Escherichia coli O157:H7. https://stacks.cdc.gov/view/cdc/15940
Tserenpuntsag, Boldtsetseg, Hwa-Gan Chang, Perry F. Smith, and Dale L. Morse. Hemolytic Uremic Syndrome Risk and Escherichia coli O157:H7. 2005. https://stacks.cdc.gov/view/cdc/15940.
Tserenpuntsag, Boldtsetseg, et al. Hemolytic Uremic Syndrome Risk and Escherichia coli O157:H7. 2005, Stacks. https://stacks.cdc.gov/view/cdc/15940.
The number of dog-mediated rabies cases in China has increased exponentially; the number of human deaths has been high, primarily in poor, rural communities. We review the incidence of rabies in China based on data from 1950 and 2004, obtained mainly from epidemiologic bulletins published by the Chinese Ministry of Health.
Supporting FilesPublic Domain
Tang, X., Luo, M., Zhang, S., Fooks, A. R., Hu, R., & Tu, C. (2005). Pivotal Role of Dogs in Rabies Transmission, China. https://stacks.cdc.gov/view/cdc/15872
Tang, Xianchun, Ming Luo, Shuyi Zhang, Anthony R. Fooks, Rongliang Hu, and Changchun Tu. Pivotal Role of Dogs in Rabies Transmission, China. 2005. https://stacks.cdc.gov/view/cdc/15872.
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