Rapid Screening Evaluation of SARS-CoV-2 IgG Assays Using Z-Scores to Standardize Results

Das, Marie K.; Chaudhary, Anu; Bryan, Andrew; Wener, Mark H.; Fink, Susan L.; Morishima, Chihiro

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Rapid Screening Evaluation of SARS-CoV-2 IgG Assays Using Z-Scores to Standardize Results

Supporting Files Public Domain

July 29 2020
By Das, Marie K. ; Chaudhary, Anu ; Bryan, Andrew ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Das, Marie K. ; Chaudhary, Anu ; Bryan, Andrew ; Wener, Mark H. ; Fink, Susan L. ; Morishima, Chihiro
Description:

Many serologic tests are now available for measuring severe acute respiratory syndrome coronavirus 2 antibodies to evaluate potential protective immunity and for seroprevalence studies. We describe an approach to standardizing positivity thresholds and quantitative values for different assays that uses z-scores to enable rapid and efficient comparison of serologic test performance.
Subjects:

Antibodies, Viral Betacoronavirus Clinical Laboratory Techniques Coronavirus Infections Covid-19 Humans Immunoglobulin G Mass Screening Pandemics Pneumonia, Viral Reproducibility Of Results Serologic Tests
Source:

Emerg Infect Dis. 26(10):2501-2503
Pubmed ID:

32723430
Pubmed Central ID:

PMC7510736
Document Type:

Journal Article
Genre:

Letter
Volume:

26
Issue:

10
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:ce046582654861bf7b53ff5f3e8093e9aa3788e4a124ff3a92dc511738041531
Download URL:

https://stacks.cdc.gov/view/cdc/94786/cdc_94786_DS1.pdf
File Type:

[PDF - 736.57 KB ]

File Language:

English

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