Clinicopathologic and Immunohistochemical Findings from Autopsy of Patient with COVID-19, Japan

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Adachi, Takuya ; Chong, Ja-Mun ; Nakajima, Noriko ; Sano, Masahiro ; Yamazaki, Jun ; Miyamoto, Ippei ; Nishioka, Haruka ; Akita, Hidetaka ; Sato, Yuko ; Kataoka, Michiyo ; Katano, Harutaka ; Tobiume, Minoru ; Sekizuka, Tsuyoshi ; Itokawa, Kentaro ; Kuroda, Makoto ; Suzuki, Tadaki
• Description:
  An autopsy of a patient in Japan with coronavirus disease indicated pneumonia lung pathology, manifested as diffuse alveolar damage. We detected severe acute respiratory syndrome coronavirus 2 antigen in alveolar epithelial cells and macrophages. Coronavirus disease is essentially a lower respiratory tract disease characterized by direct viral injury of alveolar epithelial cells.
• Subjects:
  Aged, 80 And Over Alveolar Epithelial Cells Autopsy Betacoronavirus Clinicopathologic And Immunohistochemical Findings From Autopsy Of Patient With Covid-19, Japan Coronavirus Disease Coronavirus Infections Covid-19 Cruise Diffuse Alveolar Damage Dispatch Electron Microscopy Female Humans Immunohistochemistry Japan Lung Next-Generation Sequencing Pandemics Pneumonia, Viral Respiratory Infections Sars-Cov-2 Severe Acute Respiratory Syndrome Coronavirus 2 Viruses Zoonoses

  More +
• Source:
  Emerg Infect Dis. 26(9):2157-2161
• Pubmed ID:
  32412897
• Pubmed Central ID:
  PMC7454070
• Document Type:
  Journal Article
• Volume:
  26
• Issue:
  9
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:d77b8aeb0ea712e111d50f94131b7df80bea7551506e203386e60522b4aee1b2
• Download URL:
  https://stacks.cdc.gov/view/cdc/93006/cdc_93006_DS1.pdf
• File Type:
  [PDF - 1.60 MB ]