Characterizing Norovirus Transmission from Outbreak Data, United States

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Steele, Molly K. ; Wikswo, Mary E. ; Hall, Aron J. ; Koelle, Katia ; Handel, Andreas ; Levy, Karen ; Waller, Lance A. ; Lopman, Ben A.
• Description:
  Norovirus is the leading cause of acute gastroenteritis outbreaks in the United States. We estimated the basic (R|) and effective (R|) reproduction numbers for 7,094 norovirus outbreaks reported to the National Outbreak Reporting System (NORS) during 2009-2017 and used regression models to assess whether transmission varied by outbreak setting. The median R| was 2.75 (interquartile range [IQR] 2.38-3.65), and median R| was 1.29 (IQR 1.12-1.74). Long-term care and assisted living facilities had an R| of 3.35 (95% CI 3.26-3.45), but R| did not differ substantially for outbreaks in other settings, except for outbreaks in schools, colleges, and universities, which had an R| of 2.92 (95% CI 2.82-3.03). Seasonally, R| was lowest (3.11 [95% CI 2.97-3.25]) in summer and peaked in fall and winter. Overall, we saw little variability in transmission across different outbreaks settings in the United States.
• Subjects:
  Caliciviridae Infections Disease Outbreaks Foodborne Diseases Gastroenteritis Humans Norovirus Seasons
• Source:
  Emerg Infect Dis. 26(8):1818-1825
• Pubmed ID:
  32687043
• Pubmed Central ID:
  PMC7392428
• Document Type:
  Journal Article
• Place as Subject:
  United States
• Location:
  North America
• Volume:
  26
• Issue:
  8
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:1fd1b1d0bbab06b76a55eee7cec8e8b0991939bef77f3b6a64e8966530649241
• Download URL:
  https://stacks.cdc.gov/view/cdc/91535/cdc_91535_DS1.pdf
• File Type:
  [PDF - 746.46 KB ]