Emergence of Novel Norovirus GII.4 Variant

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Chhabra, Preeti ; Tully, Damien C. ; Mans, Janet ; Niendorf, Sandra ; Barclay, Leslie ; Cannon, Jennifer L. ; Montmayeur, Anna M. ; Pan, Chao-Yang ; Page, Nicola ; Williams, Rachel ; Tutill, Helena ; Roy, Sunando ; Celma, Cristina ; Beard, Stuart ; Mallory, Michael L. ; Manouana, Gédéon Prince ; Velavan, Thirumalaisamy P. ; Adegnika, Ayola Akim ; Kremsner, Peter G. ; Lindesmith, Lisa C. ; Hué, Stéphane ; Baric, Ralph S. ; Breuer, Judith ; Vinjé, Jan
• Description:
  We detected a novel GII.4 variant with an amino acid insertion at the start of epitope A in viral protein 1 of noroviruses from the United States, Gabon, South Africa, and the United Kingdom collected during 2017-2022. Early identification of GII.4 variants is crucial for assessing pandemic potential and informing vaccine development.
• Subjects:
  Caliciviridae Infections Gastroenteritis Genotype Humans Norovirus Pandemics Phylogeny
• Keywords:
  Acute Gastroenteritis Enteric Infections Norovirus Viruses
• Source:
  Emerg Infect Dis. 2024; 30(1):163-167
• Pubmed ID:
  38063078
• Pubmed Central ID:
  PMC10756382
• Document Type:
  Journal Article
• Funding:
  WT_/Wellcome TrustUnited Kingdom/ ; R01 AI148260/AI/NIAID NIH HHSUnited States/
• Place as Subject:
  United States ; United Kingdom ; South Africa
• Volume:
  30
• Issue:
  1
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:9cd0a381365539817db57fdb9b67ee6ef3f228575b8a428caf1472e160f43c58
• Download URL:
  https://stacks.cdc.gov/view/cdc/140581/cdc_140581_DS1.pdf
• File Type:
  [PDF - 1.38 MB ]